Whole-heart modeling: applications to cardiac electrophysiology and electromechanics

NA Trayanova - Circulation research, 2011 - Am Heart Assoc
Recent developments in cardiac simulation have rendered the heart the most highly
integrated example of a virtual organ. We are on the brink of a revolution in cardiac …

[HTML][HTML] Multi-scale computational modelling in biology and physiology

J Southern, J Pitt-Francis, J Whiteley, D Stokeley… - Progress in biophysics …, 2008 - Elsevier
Recent advances in biotechnology and the availability of ever more powerful computers
have led to the formulation of increasingly complex models at all levels of biology. One of the …

Fully coupled fluid‐electro‐mechanical model of the human heart for supercomputers

A Santiago, J Aguado‐Sierra… - … journal for numerical …, 2018 - Wiley Online Library
In this work, we present a fully coupled fluid‐electro‐mechanical model of a 50th percentile
human heart. The model is implemented on Alya, the BSC multi‐physics parallel code …

Electromechanics of the heart: a unified approach to the strongly coupled excitation–contraction problem

S Göktepe, E Kuhl - Computational mechanics, 2010 - Springer
This manuscript is concerned with a novel, unified finite element approach to fully coupled
cardiac electromechanics. The intrinsic coupling arises from both the excitation-induced …

Coupling of a 3D finite element model of cardiac ventricular mechanics to lumped systems models of the systemic and pulmonic circulation

RCP Kerckhoffs, ML Neal, Q Gu… - Annals of biomedical …, 2007 - Springer
In this study we present a novel, robust method to couple finite element (FE) models of
cardiac mechanics to systems models of the circulation (CIRC), independent of cardiac …

Models of cardiac electromechanics based on individual hearts imaging data: image-based electromechanical models of the heart

V Gurev, T Lee, J Constantino, H Arevalo… - … and modeling in …, 2011 - Springer
Current multi-scale computational models of ventricular electromechanics describe the full
process of cardiac contraction on both the micro-and macro-scales including: the …

[图书][B] Geometric modeling and mesh generation from scanned images

YJ Zhang - 2018 - taylorfrancis.com
Cutting-Edge Techniques to Better Analyze and Predict Complex Physical Phenomena
Geometric Modeling and Mesh Generation from Scanned Images shows how to integrate …

[HTML][HTML] Cardiac electromechanical models: from cell to organ

NA Trayanova, JJ Rice - Frontiers in physiology, 2011 - frontiersin.org
The heart is a multiphysics and multiscale system that has driven the development of the
most sophisticated mathematical models at the frontiers of computational physiology and …

Simulation of the 3D hyperelastic behavior of ventricular myocardium using a finite-element based neural-network approach

W Zhang, DS Li, T Bui-Thanh, MS Sacks - Computer methods in applied …, 2022 - Elsevier
High-fidelity cardiac models using attribute-rich finite element based models have been
developed to a very mature stage. However, such finite-element based approaches remain …

Multiscale modeling for biologists

M Meier‐Schellersheim, IDC Fraser… - … : Systems Biology and …, 2009 - Wiley Online Library
Biomedical research frequently involves performing experiments and developing
hypotheses that link different scales of biological systems such as, for instance, the scales of …