Noninvasive reconstruction of the three-dimensional ventricular activation sequence during pacing and ventricular tachycardia in the canine heart

C Han, SM Pogwizd… - American Journal of …, 2012 - journals.physiology.org
Single-beat imaging of myocardial activation promises to aid in both cardiovascular
research and clinical medicine. In the present study we validate a three-dimensional (3D) …

Modeling cardiac mechano-electrical feedback using reaction-diffusion-mechanics systems

RH Keldermann, MP Nash, AV Panfilov - Physica D: Nonlinear Phenomena, 2009 - Elsevier
In many practically important cases, wave propagation described by the reaction-diffusion
equation initiates deformation of the medium. Mathematically, such processes are described …

Mathematical modeling for keloid formation triggered by virus: malignant effects and immune system competition

C Bianca - Mathematical Models and Methods in Applied …, 2011 - World Scientific
This paper deals with the modeling of a wound healing disease, the keloid, which may
provoke onset of malignant cells with higher progression feature, thus generating cells with …

Modeling of cardiac growth and remodeling of myofiber orientation

PHM Bovendeerd - Journal of biomechanics, 2012 - Elsevier
The heart has the ability to respond to long-term changes in its environment through
changes in mass (growth), shape (morphogenesis) and tissue properties (remodeling). For …

Primal-mixed formulations for reaction–diffusion systems on deforming domains

R Ruiz-Baier - Journal of Computational Physics, 2015 - Elsevier
We propose a finite element formulation for a coupled elasticity–reaction–diffusion system
written in a fully Lagrangian form and governing the spatio-temporal interaction of species …

Fully Eulerian finite element approximation of a fluid‐structure interaction problem in cardiac cells

A Laadhari, R Ruiz‐Baier… - International journal for …, 2013 - Wiley Online Library
We propose in this paper an Eulerian finite element approximation of a coupled chemical
fluid‐structure interaction problem arising in the study of mesoscopic cardiac biomechanics …

A framework for biomechanics simulations using four-chamber cardiac models

A Jafari, E Pszczolkowski, A Krishnamurthy - Journal of biomechanics, 2019 - Elsevier
Computational cardiac models have been extensively used to study different cardiac
biomechanics; specifically, finite-element analysis has been one of the tools used to study …

Cardiac and renal function interactions in heart failure with reduced ejection fraction: A mathematical modeling analysis

H Yu, S Basu, KM Hallow - PLoS computational biology, 2020 - journals.plos.org
Congestive heart failure is characterized by suppressed cardiac output and arterial filling
pressure, leading to renal retention of salt and water, contributing to further volume overload …

Heart-on-chip for combined cellular dynamics measurements and computational modeling towards clinical applications

J Park, Z Wu, PR Steiner, B Zhu, JXJ Zhang - Annals of Biomedical …, 2022 - Springer
Organ-on-chip or micro-engineered three-dimensional cellular or tissue models are
increasingly implemented in the study of cardiovascular pathophysiology as alternatives to …

Theoretic impact of infarct compliance on left ventricular function

JJ Pilla, JH Gorman III, RC Gorman - The Annals of thoracic surgery, 2009 - Elsevier
BACKGROUND: After coronary occlusion, the infarct region loses contractile function
immediately and then undergoes a progressive healing process. This causes complex and …