Oligonucleotide-based therapies are advanced novel interventions used in the management
of various respiratory diseases such as asthma and Chronic Obstructive Pulmonary Disease …

Recent research in the vaccine and immunotherapy fields has revealed that biomaterials
have the ability to activate immune pathways, even in the absence of other immune …

abstract Due to the excellent safety profile of poly (D, L-lactide-co-glycolide)(PLGA) particles
in human, and their biodegradability, many studies have focused on the application of PLGA …

Nanovaccine‐based immunotherapy (NBI) has received greater attention recently for its
potential to prime tumor‐specific immunity and establish a long‐term immune memory that …

Lung diseases, including COVID-19 and lung cancers, is a huge threat to human health.
However, for the treatment and diagnosis of various lung diseases, such as pneumonia …

Unmethylated cytosine-guanine dinucleotide-containing oligodeoxynucleotides (CpG
ODNs), which are synthetic agonists of Toll-like receptor 9 (TLR9), activate humoral and …

Poly (lactic-co-glycolic acid)(PLGA) particles are a widely used and extensively studied drug
delivery system. The favorable properties of PLGA such as good bioavailability, controlled …

Asthma is a chronic lung disease affecting millions worldwide. While classically
acknowledged to result from allergen-driven type 2 inflammatory responses leading to IgE …

The recent progress in harnessing the efficient and precise method of DNA editing provided
by CRISPR/Cas9 is one of the most promising major advances in the field of gene therapy …

Synthetic imidazoquinoline-based toll-like receptor (TLR) 7/8 bi-specific agonists are
promising vaccine adjuvants that can induce maturation of dendritic cells (DCs) and activate …