Nanoparticle impact on innate immune cell pattern-recognition receptors and inflammasomes activation
Nanotechnology-based strategies can dramatically impact the treatment, prevention and
diagnosis of a wide range of diseases. Despite the unprecedented success achieved with …
diagnosis of a wide range of diseases. Despite the unprecedented success achieved with …
[HTML][HTML] Protein corona–mediated targeting of nanocarriers to B cells allows redirection of allergic immune responses
L Shen, S Tenzer, W Storck, D Hobernik… - Journal of Allergy and …, 2018 - Elsevier
Background Nanoparticle (NP)–based vaccines are attractive immunotherapy tools because
of their capability to codeliver antigen and adjuvant to antigen-presenting cells. Their cellular …
of their capability to codeliver antigen and adjuvant to antigen-presenting cells. Their cellular …
Recent advances in the use of nanoparticles for allergen‐specific immunotherapy
The number of patients suffering from allergic asthma and rhinoconjunctivitis has increased
dramatically within the last decades. Allergen‐specific immunotherapy (AIT) is the only …
dramatically within the last decades. Allergen‐specific immunotherapy (AIT) is the only …
Immunomodulatory Effects of Subacute Inhalation Exposure to Copper Oxide Nanoparticles in House Dust Mite-Induced Asthma
S Areecheewakul, A Adamcakova-Dodd… - ACS …, 2023 - ACS Publications
It has been shown that inhalation exposure to copper oxide nanoparticles (CuO NPs) results
in pulmonary inflammation. However, immunomodulatory consequences after CuO NP …
in pulmonary inflammation. However, immunomodulatory consequences after CuO NP …
Allergen immunotherapy: progress and future outlook
L Šošić, M Paolucci, S Flory, F Jebbawi… - Expert Review of …, 2023 - Taylor & Francis
Introduction Allergy, the immunological hypersensitivity to innocuous environmental
compounds, is a global health problem. The disease triggers, allergens, are mostly proteins …
compounds, is a global health problem. The disease triggers, allergens, are mostly proteins …
[HTML][HTML] Recent advances in nanomaterials for asthma treatment
X Zuo, X Guo, Y Gu, H Zheng, Z Zhou, X Wang… - International Journal of …, 2022 - mdpi.com
Asthma is a chronic airway inflammatory disease with complex mechanisms, and these
patients often encounter difficulties in their treatment course due to the heterogeneity of the …
patients often encounter difficulties in their treatment course due to the heterogeneity of the …
Clinical use of adjuvants in allergen-immunotherapy
L Klimek, CB Schmidt-Weber, MF Kramer… - Expert review of …, 2017 - Taylor & Francis
ABSTRACT Introduction: Allergen-specific Immunotherapy (AIT) is the only available
treatment aimed to tackle the underlying causes of allergy. The active components of …
treatment aimed to tackle the underlying causes of allergy. The active components of …
Polyester as antigen carrier toward particulate vaccines
M Gonzalez-Miro, S Chen, ZJ Gonzaga… - …, 2019 - ACS Publications
Spherical polyhydroxyalkanoate (PHA) inclusions are naturally self-assembled inside
bacteria. These PHA beads are shell–core structures composed of a hydrophobic PHA core …
bacteria. These PHA beads are shell–core structures composed of a hydrophobic PHA core …
Airway epithelial-targeted nanoparticles for asthma therapy
Asthma is a common chronic inflammatory disease associated with intermittent airflow
obstruction caused by airway inflammation, mucus overproduction, and bronchial …
obstruction caused by airway inflammation, mucus overproduction, and bronchial …
Impact of molecular weight on the intrinsic immunogenic activity of poly (beta amino esters)
JI Andorko, KG Pineault… - Journal of Biomedical …, 2017 - Wiley Online Library
Polymeric carriers are ubiquitously studied in vaccine and drug delivery to control the
encapsulation, kinetics, and targeting of cargo. Recent research reveals many polymers can …
encapsulation, kinetics, and targeting of cargo. Recent research reveals many polymers can …