[HTML][HTML] Nanoparticle conjugation enhances the immunomodulatory effects of intranasally delivered CpG in house dust mite-allergic mice

M Ballester, L Jeanbart, A De Titta, C Nembrini… - Scientific reports, 2015 - nature.com
An emerging strategy in preventing and treating airway allergy consists of modulating the
immune response induced against allergens in the lungs. CpG oligodeoxynucleotides have …

Nanotechnology-based therapeutics for targeting inflammatory lung diseases

CY Loo, WH Lee - Nanomedicine, 2022 - Future Medicine
The physiochemical properties of drugs used in treating inflammation-associated lung
diseases (ie, asthma, chronic obstructive pulmonary disease, pulmonary fibrosis) play an …

Evaluation of size and dose effects of rChe a 3 allergen loaded PLGA nanoparticles on modulation of Th2 immune responses by sublingual immunotherapy in mouse …

J Hajavi, M Hashemi, M Sankian - International journal of pharmaceutics, 2019 - Elsevier
Allergic rhinitis (AR) is the most common respiratory allergic disorder which results from an
IgE-mediated inflammation in the nasal mucosa. The first strategies for the controlling of AR …

Nanoparticle–allergen complexes for allergen immunotherapy

G Di Felice, P Colombo - International journal of nanomedicine, 2017 - Taylor & Francis
Allergen-specific immunotherapy was introduced in clinical settings more than 100 years
ago. It remains the only curative approach to treating allergic disorders that ameliorates …

Nanoparticles in allergen immunotherapy

A Longo, V Longo, P Colombo - Current Opinion in Allergy and …, 2021 - journals.lww.com
Nanoparticles in allergen immunotherapy : Current Opinion in Allergy and Clinical Immunology
Nanoparticles in allergen immunotherapy : Current Opinion in Allergy and Clinical Immunology …

Diaminosulfide based polymer microparticles as cancer vaccine delivery systems

SM Geary, Q Hu, VB Joshi, NB Bowden… - Journal of controlled …, 2015 - Elsevier
The aim of the research presented here was to determine the characteristics and
immunostimulatory capacity, in vivo, of antigen and adjuvant co-loaded into microparticles …

A20-OVA nanoparticles inhibit allergic asthma in a murine model

XQ Luo, JW Zhong, SY Qiu, M Zhi, LQ Yang, YL Zhou… - Inflammation, 2020 - Springer
The skewed T helper (Th) 2 response plays a critical role in the pathogenesis of allergic
asthma. Regulatory T (Treg) cells and the regulatory cytokines are required in maintaining …

The use of adjuvants for enhancing allergen immunotherapy efficacy

J Chesné, CB Schmidt-Weber… - … and Allergy Clinics, 2016 - immunology.theclinics.com
Allergic diseases are characterized by the seasonally recurring production of T helper 2
(TH2) cytokines (eg, Interleukin [IL]-4, IL-5, and IL-13), which drive the production of allergen …

Nanoparticle-based CpG-oligonucleotide therapy for treating allergic asthma

BE Givens, SM Geary, AK Salem - Immunotherapy, 2018 - Future Medicine
Allergic asthma is becoming increasingly prevalent in the developed world, and many
common allergens are capable of inducing allergic asthma responses, particularly in atopic …

A pilot study evaluating combinatorial and simultaneous delivery of polyethylenimine-plasmid DNA complexes encoding for VEGF and PDGF for bone regeneration in …

SR D'Mello, S Elangovan, L Hong… - Current …, 2015 - ingentaconnect.com
Gene therapy is a promising strategy to deliver growth factors of interest locally in a
sustained fashion and has the potential to overcome barriers to using recombinant protein …