To develop an antibody (Ab) therapeutic against staphylococcal enterotoxin B (SEB), a
potential incapacitating bioterrorism agent and a major cause of food poisoning, we …

Staphylococcal enterotoxin B (SEB), a shock-inducing exotoxin synthesized by
Staphylococcus aureus, is an important cause of food poisoning and is a class B …

Staphylococcal enterotoxin B (SEB) is one of a family of toxins secreted by Staphylococcus
aureus that act as superantigens, activating a large fraction of the T-cell population and …

This article reports the design of a bivalent protein ligand with dual use in therapy and
diagnosis of anthrax caused by Bacillus anthracis. The ligand specifically binds to PA and …

The emergence of pathogens and toxins with resistance against conventional drugs,
vaccines, and host defense peptides and proteins warrants novel countermeasures that can …

Toxic shock syndrome (TSS), a life-threatening illness, is caused by excessively high
concentrations of proinflammatory cytokines released after superantigen stimulation of T-cell …

Superantigens (SAgs) are a family of highly potent immunostimulatory proteins produced by
bacteria or viruses. The family includes many proteins that may be unrelated by sequence or …