Key considerations to reduce or address respondent burden in patient-reported outcome (PRO) data collection

OL Aiyegbusi, J Roydhouse, SC Rivera… - Nature …, 2022 - nature.com
Patient-reported outcomes (PROs) are used in clinical trials to provide evidence of the
benefits and risks of interventions from a patient perspective and to inform regulatory …

International standards for the analysis of quality-of-life and patient-reported outcome endpoints in cancer randomised controlled trials: recommendations of the …

C Coens, M Pe, AC Dueck, J Sloan, E Basch… - The Lancet …, 2020 - thelancet.com
Summary Patient-reported outcomes (PROs), such as symptoms, function, and other health-
related quality-of-life aspects, are increasingly evaluated in cancer randomised controlled …

SPIRIT-PRO Extension explanation and elaboration: guidelines for inclusion of patient-reported outcomes in protocols of clinical trials

M Calvert, M King, R Mercieca-Bebber, O Aiyegbusi… - BMJ open, 2021 - bmjopen.bmj.com
Patient-reported outcomes (PROs) are used in clinical trials to provide valuable evidence on
the impact of disease and treatment on patients' symptoms, function and quality of life. High …

The impact of patient-reported outcome (PRO) data from clinical trials: a systematic review and critical analysis

SC Rivera, DG Kyte, OL Aiyegbusi, AL Slade… - Health and quality of life …, 2019 - Springer
Abstract Background Patient-reported outcomes (PROs) are commonly collected in clinical
trials and should provide impactful evidence on the effect of interventions on patient …

The role of patient-reported outcome measures in trials of artificial intelligence health technologies: a systematic evaluation of ClinicalTrials. gov records (1997–2022)

FJ Pearce, SC Rivera, X Liu, E Manna… - The Lancet Digital …, 2023 - thelancet.com
The extent to which patient-reported outcome measures (PROMs) are used in clinical trials
for artificial intelligence (AI) technologies is unknown. In this systematic evaluation, we aim …

Ethical considerations for the inclusion of patient-reported outcomes in clinical research: the PRO ethics guidelines

SC Rivera, OL Aiyegbusi, J Ives, H Draper… - Jama, 2022 - jamanetwork.com
Importance Patient-reported outcomes (PROs) can inform health care decisions, regulatory
decisions, and health care policy. They also can be used for audit/benchmarking and …

An urgent call to raise the bar in oncology

JJB Schnog, MJ Samson, ROB Gans… - British journal of cancer, 2021 - nature.com
Important breakthroughs in medical treatments have improved outcomes for patients
suffering from several types of cancer. However, many oncological treatments approved by …

[HTML][HTML] Past and current practice of patient-reported outcome measurement in randomized cancer clinical trials: a systematic review

JM Giesinger, F Efficace, N Aaronson, M Calvert… - Value in Health, 2021 - Elsevier
Objectives In our systematic review, we assessed past and current practice of patient-
reported outcome (PRO) measurement in cancer randomized, controlled trials (RCTs) …

The future of clinical trial design in oncology

A Spreafico, AR Hansen, AR Abdul Razak, PL Bedard… - Cancer discovery, 2021 - AACR
Clinical trials represent a fulcrum for oncology drug discovery and development to bring safe
and effective medicines to patients in a timely manner. Clinical trials have shifted from …

Priorities for the global advancement of care for older adults with cancer: an update of the International Society of Geriatric Oncology Priorities Initiative

M Extermann, E Brain, B Canin, MN Cherian… - The Lancet …, 2021 - thelancet.com
Summary In 2011, the International Society of Geriatric Oncology (SIOG) published the SIOG
10 Priorities Initiative, which defined top priorities for the improvement of the care of older …