Antimicrobial resistance in ESKAPE pathogens

DMP De Oliveira, BM Forde, TJ Kidd… - Clinical microbiology …, 2020 - Am Soc Microbiol
Antimicrobial-resistant ESKAPE (E nterococcus faecium, S taphylococcus aureus, K
lebsiella pneumoniae, A cinetobacter baumannii, P seudomonas aeruginosa, and E …

Biofilms as promoters of bacterial antibiotic resistance and tolerance

C Uruén, G Chopo-Escuin, J Tommassen… - Antibiotics, 2020 - mdpi.com
Multidrug resistant bacteria are a global threat for human and animal health. However, they
are only part of the problem of antibiotic failure. Another bacterial strategy that contributes to …

Enterobacter spp.: Update on Taxonomy, Clinical Aspects, and Emerging Antimicrobial Resistance

A Davin-Regli, JP Lavigne… - Clinical microbiology …, 2019 - Am Soc Microbiol
The genus Enterobacter is a member of the ESKAPE group, which contains the major
resistant bacterial pathogens. First described in 1960, this group member has proven to be …

Porins and small-molecule translocation across the outer membrane of Gram-negative bacteria

J Vergalli, IV Bodrenko, M Masi, L Moynié… - Nature Reviews …, 2020 - nature.com
Gram-negative bacteria and their complex cell envelope, which comprises an outer
membrane and an inner membrane, are an important and attractive system for studying the …

Outer membrane protein A (OmpA) as a potential therapeutic target for Acinetobacter baumannii infection

D Nie, Y Hu, Z Chen, M Li, Z Hou, X Luo, X Mao… - Journal of biomedical …, 2020 - Springer
Acinetobacter baumannii (A. baumannii) is an important opportunistic pathogen causing
serious nosocomial infections, which is considered as the most threatening Gram-negative …

[HTML][HTML] Global spread of carbapenem-resistant Enterobacteriaceae: Epidemiological features, resistance mechanisms, detection and therapy

J Ma, X Song, M Li, Z Yu, W Cheng, Z Yu… - Microbiological …, 2023 - Elsevier
Bacterial drug resistance has become a global public health threat, among which the
infection of carbapenem-resistant Enterobacterales (CRE) is one of the top noticeable …

Class C β-lactamases: molecular characteristics

A Philippon, G Arlet, R Labia… - Clinical microbiology …, 2022 - Am Soc Microbiol
Class C β-lactamases or cephalosporinases can be classified into two functional groups (1,
1e) with considerable molecular variability (≤ 20% sequence identity). These enzymes are …

Gram-Negative Bacteria Holding Together in a Biofilm: The Acinetobacter baumannii Way

A Pompilio, D Scribano, M Sarshar, G Di Bonaventura… - Microorganisms, 2021 - mdpi.com
Bacterial biofilms are a serious public-health problem worldwide. In recent years, the rates of
antibiotic-resistant Gram-negative bacteria associated with biofilm-forming activity have …

[HTML][HTML] “Superbugs” with hypervirulence and carbapenem resistance in Klebsiella pneumoniae: the rise of such emerging nosocomial pathogens in China

D Pu, J Zhao, K Chang, X Zhuo, B Cao - Science Bulletin, 2023 - Elsevier
Although hypervirulent Klebsiella pneumoniae (hvKP) can produce community-acquired
infections that are fatal in young and adult hosts, such as pyogenic liver abscess …

Design and simulation of the liposomal model by using a coarse-grained molecular dynamics approach towards drug delivery goals

J Parchekani, A Allahverdi, M Taghdir… - Scientific Reports, 2022 - nature.com
The simulated liposome models provide events in molecular biological science and cellular
biology. These models may help to understand the cell membrane mechanisms, biological …