The amphetamine derivative (±)-3, 4-methylenedioxymethamphetamine (MDMA, ecstasy) is
a popular recreational drug among young people, particularly those involved in the dance …

Several aspects of airway function are under autonomic control: airway smooth muscle tone,
submucosal gland secretion, epithelial cell function, bronchial vascular tone and …

Vasoactive intestinal polypeptide (VIP), a 28 amino acid peptide hormone, plays many
physiological roles in the peripheral and central nerve systems. A functional cDNA clone of …

The molecular basis for the known intramembrane receptor/receptor interactions among G
protein-coupled receptors was postulated to be heteromerization based on receptor subtype …

The cholinergic innervation of rat cerebral cortex was studied by immunohistochemical
localization of choline acetyltransferase. Stained bipolar cells, fibers and terminals were …

Within the past decade, a large number of peptides have been described within the
vertebrate central nervous system. Some of these peptides were previously known to be …

Recent evidence suggests that biologically active polypeptides are present in certain
populations of neurons which also contain classical transmitters such as noradrenaline (NA) …

Neural activity generates increases in extracellular K+ concentration,[K+] 0, which must be
regulated in order to maintain normal brain function1. Glial cells are thought to play an …

The existence of cholinergic neuronal cell bodies in mammalian cerebral cortex was long
the subject of much controversy (see ref. 1 for review). Recently, however, a specific …

In the mammalian brain, a major regulatory peptide is vasoactive intestinal peptide (VIP).
This 28 amino acid peptide, originally isolated from the porcine duodenum, was later found …