Cancer therapy-induced heart injury is a significant concern for cancer patients undergoing
chemotherapy, radiotherapy, immunotherapy, and also targeted molecular therapy. The use …

Chemotherapy is a main treatment for cancer, and it benefits patients by controlling cancer
relapse and metastasis, thereby leading to an increase in the overall survival rate. However …

Mitochondrial dysfunction may lead to cardiomyocyte death in trastuzumab (TZM)-induced
cardiotoxicity. Accordingly, this study was designed to evaluate the mitochondrial protective …

Cyclophosphamide is an alkylating agent used in the treatment of various types of tumors
and autoimmune diseases. Unfortunately, cyclophosphamide usage is limited in clinical …

Although several investigations have demonstrated the beneficial effects of chrysin (CH),
there is limited information on its supportive effects on rainbow trout (Oncorhynchus mykiss) …

Cardiotoxicity is a serious complication of cancer therapy. It is the second leading cause of
morbidity and mortality in cancer survivors and is associated with a variety of factors …

Rosmarinic acid (RA) has various pharmacological effects, such as hypolipidemic and
antitumor effects; however, its role in immunomodulation is not fully understood. Therefore …

This present study investigated the protective effects of asperuloside (ASP) against cadmium-
induced nephrocardiac toxicity. Rats were treated with 50 mg/kg of ASP for five weeks and …

Background Cyclophosphamide (CP) is a commonly used chemotherapeutic and
immunosuppressive alkylating agent. However, cardiac adverse effects of CP interfere with …

In the present study, we investigated the protective effect of magnolin (MAG) against
oxidative stress induced by cyclophosphamide (CP) and its role in the Nrf2/HO-1 signaling …