People are living to older age. Falls constitute a leading cause of injuries, hospitalization
and deaths among the elderly. Older people fall more often for a variety of reasons …

People with severe mental illness have a considerably shorter lifespan than the general
population. This excess mortality is mainly due to physical illness. Next to mental illness …

Our systematic review and meta-analysis of observational studies indicated that the use of
antipsychotics was associated with a nearly 1.5-fold increase in the risk of fracture. First …

Background: polypharmacy is an important risk factor for falls, but recent studies suggest
only when including medications associated with increasing the risk of falls. Design: a …

Purpose Anxiolytics and hypnotics are widely used and may cause injurious falls. We aimed
to examine associations between exposure to anxiolytics and hypnotics and the risk of hip …

Benzodiazepines (BZDs) are some of the most commonly prescribed drugs in the world. It
has been shown that BZD use could be associated with increased fracture risk. However …

It has been shown that antidepressants would have a direct action on bone metabolism and
would be associated with increased fracture risk. Results from this large meta-analysis show …

Article-at-a-Glance Background Patient falls are among the most commonly reported
adverse hospital events with more than one million occurring annually in the United States; …

Context Computerized drug alerts for psychotropic drugs are expected to reduce fall-related
injuries in older adults. However, physicians over-ride most alerts because they believe the …

Background Hypnosedatives are commonly prescribed for anxiety and sleep problems.
Changes in pharmacokinetics and pharmacodynamics of benzodiazepines (BZDs) during …