[HTML][HTML] Clonal multi-omics reveals Bcor as a negative regulator of emergency dendritic cell development
Despite advances in single-cell multi-omics, a single stem or progenitor cell can only be
tested once. We developed clonal multi-omics, in which daughters of a clone act as …
tested once. We developed clonal multi-omics, in which daughters of a clone act as …
[HTML][HTML] Ly6D+Siglec-H+ precursors contribute to conventional dendritic cells via a Zbtb46+Ly6D+ intermediary stage
K Lutz, A Musumeci, C Sie, E Dursun… - Nature …, 2022 - nature.com
Plasmacytoid and conventional dendritic cells (pDC and cDC) are generated from
progenitor cells in the bone marrow and commitment to pDCs or cDC subtypes may occur in …
progenitor cells in the bone marrow and commitment to pDCs or cDC subtypes may occur in …
[HTML][HTML] Immune response and treatment targets of chronic hepatitis B virus infection: Innate and adaptive immunity
P Zheng, Y Dou, Q Wang - Frontiers in Cellular and Infection …, 2023 - frontiersin.org
Chronic hepatitis B virus (HBV) infection is a major global public health risk that threatens
human life and health, although the number of vaccinated people has increased. The …
human life and health, although the number of vaccinated people has increased. The …
[HTML][HTML] Animal Models of Cryptococcus neoformans in Identifying Immune Parameters Associated With Primary Infection and Reactivation of Latent Infection
TG Normile, AM Bryan, M Del Poeta - Frontiers in Immunology, 2020 - frontiersin.org
Cryptococcus species are environmental fungal pathogens and the causative agents of
cryptococcosis. Infection occurs upon inhalation of infectious particles, which proliferate in …
cryptococcosis. Infection occurs upon inhalation of infectious particles, which proliferate in …
Optimization of an mRNA vaccine assisted with cyclodextrin-polyethyleneimine conjugates
Messenger RNA (mRNA) vaccines have attracted great interest in recent years due to their
high potency, safety profile, and potential of rapid development. Although a number of …
high potency, safety profile, and potential of rapid development. Although a number of …
Immunomodulatory bonds of the partnership between dendritic cells and T cells
J Bourque, D Hawiger - Critical Reviews™ in Immunology, 2018 - dl.begellhouse.com
By acquiring, processing, and presenting both foreign and self-antigens, dendritic cells
(DCs) initiate T cell activation that is shaped through the immunomodulatory functions of a …
(DCs) initiate T cell activation that is shaped through the immunomodulatory functions of a …
Absence of MHC class II on cDC1 dendritic cells triggers fatal autoimmunity to a cross-presented self-antigen
C Wohn, V Le Guen, O Voluzan, F Fiore, S Henri… - Science …, 2020 - science.org
Conventional dendritic cells expressing the XCR1 chemokine receptor (cDC1s) excel at
cross-presentation. Here, we developed and used a mouse model in which a Cre …
cross-presentation. Here, we developed and used a mouse model in which a Cre …
[HTML][HTML] Metastatic colonization: Escaping immune surveillance
J Schaller, J Agudo - Cancers, 2020 - mdpi.com
Simple Summary Metastasis is the major cause of deaths in cancer. The determinants
enabling metastatic colonization in various organs are an active field in tumor research …
enabling metastatic colonization in various organs are an active field in tumor research …
[HTML][HTML] Deciphering tumor-infiltrating dendritic cells in the single-cell era
Q Huang, F Wang, D Hao, X Li, X Li, T Lei… - … Hematology & Oncology, 2023 - Springer
Dendritic cells (DCs) serve as a pivotal link connecting innate and adaptive immunity by
processing tumor-derived antigens and activating T cells. The advent of single-cell …
processing tumor-derived antigens and activating T cells. The advent of single-cell …
[HTML][HTML] Lung CD103+ dendritic cells restrain allergic airway inflammation through IL-12 production
L Conejero, SC Khouili, S Martínez-Cano… - JCI insight, 2017 - ncbi.nlm.nih.gov
DCs are necessary and sufficient for induction of allergic airway inflammation. CD11b+ DCs
direct the underlying Th2 immunity, but debate surrounds the function of CD103+ DCs in …
direct the underlying Th2 immunity, but debate surrounds the function of CD103+ DCs in …