Next-generation DNA sequencing technology has dramatically advanced clinical oncology
through the identification of therapeutic targets and molecular biomarkers, leading to the …

Breast cancer is the most common cancer among women worldwide. Due to its complexity in
nature, effective breast cancer treatment can encounter many challenges. Traditional …

Importance A significant proportion of patients with early-stage triple-negative breast cancer
(TNBC) are treated with neoadjuvant chemotherapy. Sequencing of circulating tumor DNA …

The development of new drugs is multidisciplinary and systematic work. High-throughput
techniques based on “-omics” have driven the discovery of biomarkers in diseases and …

Carcinoma cells undergo epithelial-mesenchymal transition (EMT); however, contributions
of EMT heterogeneity to disease progression remain a matter of debate. Here, we …

Circulating tumour cells (CTCs) are rare tumour cells found in the circulatory system of
certain cancer patients. The clinical and functional significance of CTCs is still under …

The major cause of cancer-associated mortality is tumor metastasis, a disease that is far
from understood. Many studies have observed circulating tumor cells (CTCs) in patients' …

Identification of specific subtypes of circulating tumor cells in peripheral blood of cancer
patients can provide information about the biology of metastasis and improve patient …

Efforts to improve the clinical management of several cancers include finding better methods
for the quantitative and qualitative analysis of circulating tumor cells (CTCs). However …

Simple Summary Automated enumeration of circulating tumor cells (CTC) from
immunofluorescence images starts with a selection of areas containing potential CTC. The …