[HTML][HTML] Non-alcoholic fatty liver disease (NAFLD)/non-alcoholic steatohepatitis (NASH)-related liver fibrosis: mechanisms, treatment and prevention

F Tacke, R Weiskirchen - Annals of Translational Medicine, 2021 - ncbi.nlm.nih.gov
Liver fibrosis is the excessive expression and accumulation of extracellular matrix proteins in
the liver. Fibrotic scarring occurs as the consequence of chronic injury and inflammation …

Alpinetin exerts anti-inflammatory, anti-oxidative and anti-angiogenic effects through activating the Nrf2 pathway and inhibiting NLRP3 pathway in carbon tetrachloride …

Z Zhu, R Hu, J Li, X Xing, J Chen, Q Zhou… - International …, 2021 - Elsevier
Alpinetin is the major active ingredient of Alpiniakatsumadai Hayata. As a kind of novel plant-
derived flavonoid, alpinetin has shown potent hepatoprotective effect against many liver …

[HTML][HTML] METTL14 reverses liver fibrosis by inhibiting NOVA2 through an m6A-YTHDF2–dependent mechanism

X Hou, Y Li, J Song, L Peng, W Zhang… - Hepatology …, 2023 - journals.lww.com
Background: N 6-methyladenosine (m 6 A), the most prevalent internal RNA modification in
eukaryotic cells, is dynamically regulated in response to a wide range of physiological and …

[HTML][HTML] Liver stiffness and spleen stiffness predict distinct liver-related events after hepatitis C eradication with direct-acting antivirals

SH Chen, HC Lai, WP Su, JT Kao, WF Hsu… - Journal of the Formosan …, 2024 - Elsevier
Abstract Background/Purpose: This study aimed to directly compare the utility of liver
stiffness (LS) and spleen stiffness (SS) at sustained virologic response (SVR) for predicting …

Combined Liver Stiffness and Α‐fetoprotein Further beyond the Sustained Virologic Response Visit as Predictors of Long‐Term Liver‐Related Events in Patients with …

SH Chen, HC Lai, WP Su, JT Kao… - Canadian Journal of …, 2022 - Wiley Online Library
Aims. Long‐term risk stratification using combined liver stiffness (LS) and clinically relevant
blood tests acquired at the baseline further beyond the sustained virologic response (SVR) …

Liver and Spleen Stiffness Surveillance Through Elastography During and After Direct‐Acting Antiviral Therapy in Patients With Chronic Hepatitis C

SH Chen, HC Lai, WP Su, JT Kao… - … of Ultrasound in …, 2022 - Wiley Online Library
Objectives Direct‐acting antiviral agents achieve a high cure rate, resulting in early hepatic
necroinflammatory resolution and sustained fibrosis regression. This study aimed to obtain …

[PDF][PDF] The Evolution of Liver Fibrosis in Patients with Viral C Infection Post Oral Antiviral Treatment

OI Gavril, RSGF Mitu - Internal Medicine, 2022 - sciendo.com
Hepatitis C virus infection has been for several decades the major cause of cirrhosis and its
complications worldwide. However, an arsenal of new and highly effective oral direct-acting …