The clinical field of wound healing is challenged by numerous hurdles. Not only are wound‐
healing disorders complex and multifactorial, but the corresponding patient population is …

Foot ulceration is one of the most debilitating complications associated with diabetes, but its
cause remains poorly understood. Several studies have been undertaken to understand …

There is controversy as to whether or not diabetic foot infections (DFIs) caused by methicillin-
resistant Staphylococcus aureus (MRSA) are associated with worse outcomes than DFIs …

Background Infected diabetic foot ulcers (IDFU) are a major complication of diabetes
mellitus. These potentially limb-threatening ulcers are challenging to treat due to impaired …

Cutaneous microbial composition is driven by the microenvironment of the skin, as well as
by internal and external factors. Local changes in the microenvironment can affect the …

Biofilms play an important role in the development and pathogenesis of many chronic
infections. Oral biofilms, more commonly known as dental plaque, are a primary cause of …

Biofilm infection is now understood to be a potent contributor to the recalcitrant nature of
chronic wounds. Bacterial biofilms evade the host immune response and show increased …

Chronic wounds are wounds that have failed to heal after 3 months of appropriate wound
care. Previous reports have identified a diverse collection of bacteria in chronic wounds, and …

Chronic wounds fail to heal through the three normal stages of healing (inflammatory,
proliferative, and remodelling), resulting in a chronic tissue injury that is not repaired within …

Diabetic foot ulcers (DFU) contribute to 80% of lower extremity amputations. Although
physicians currently rely on clinical signs along with non‐specific biomarkers of infection …