The metastasis is a multistep process in which a small proportion of cancer cells are
detached from the colony to enter into blood cells for obtaining a new place for metastasis …

Ferroptosis is a form of regulated cell death that is initiated by excessive lipid peroxidation
that results in plasma membrane damage and the release of damage-associated molecular …

Artificial intelligence transforms drug discovery, with phenotype-based approaches
emerging as a promising alternative to target-based methods, overcoming limitations like …

Hepatocellular carcinoma (HCC) is a lethal malignancy. Although considerable efforts have
been made in recent years regarding treatments, effective therapeutic drugs for HCC remain …

Background Sustained liver fibrosis may lead to cirrhosis. Activated hepatic stellate cells
(HSCs) are crucial for liver fibrosis development. Ferroptosis, a newly iron-dependent …

Forkhead box (FOX) protein M1 (FOXM1) is a critical proliferation-associated transcription
factor (TF) that is aberrantly overexpressed in the majority of human cancers and has also …

Ferroptosis, a nonapoptotic form of programmed cell death characterized by significant iron-
dependent peroxidation of phospholipids, is regulated by cellular metabolism, redox …

The nuclear factor erythroid 2 (NF-E2)-related factor 1 (NFE2L1, also known as Nrf1) is a
highly conserved transcription factor that belongs to the CNC-bZIP subfamily. Its significance …

Over the last decade, researchers have paid more and more attention to the natural
compound curcumin for its potential application in anticancer therapy. However, the …

In ovarian tumors, the omental microenvironment profoundly influences the behavior of
cancer cells and sustains the acquisition of stem-like traits, with major impacts on tumor …