A physiologically informed strategy to effectively open, stabilize, and protect the acutely injured lung
GF Nieman, H Al-Khalisy, M Kollisch-Singule… - Frontiers in …, 2020 - frontiersin.org
Acute respiratory distress syndrome (ARDS) causes a heterogeneous lung injury and
remains a serious medical problem, with one of the only treatments being supportive care in …
remains a serious medical problem, with one of the only treatments being supportive care in …
Imaging the injured lung: mechanisms of action and clinical use
Acute respiratory distress syndrome (ARDS) consists of acute hypoxemic respiratory failure
characterized by massive and heterogeneously distributed loss of lung aeration caused by …
characterized by massive and heterogeneously distributed loss of lung aeration caused by …
Tidal changes on CT and progression of ARDS
Background Uncertain prediction of outcome in acute respiratory distress syndrome (ARDS)
impedes individual patient management and clinical trial design. Objectives To develop a …
impedes individual patient management and clinical trial design. Objectives To develop a …
Relation between respiratory mechanics, inflammation, and survival in experimental mechanical ventilation
MV Szabari, K Takahashi, Y Feng… - American journal of …, 2019 - atsjournals.org
Low–tidal volume (Vt) ventilation might protect healthy lungs from volutrauma but lead to
inflammation resulting from other mechanisms, namely alveolar derecruitment and the …
inflammation resulting from other mechanisms, namely alveolar derecruitment and the …
Hidden microatelectases increase vulnerability to ventilation-induced lung injury
K Albert, JM Krischer, A Pfaffenroth, S Wilde… - Frontiers in …, 2020 - frontiersin.org
Mechanical ventilation of lungs suffering from microatelectases may trigger the development
of acute lung injury (ALI). Direct lung injury by bleomycin results in surfactant dysfunction …
of acute lung injury (ALI). Direct lung injury by bleomycin results in surfactant dysfunction …
Looking closer at acute respiratory distress syndrome: the role of advanced imaging techniques
G Bellani, JJ Rouby, JM Constantin… - Current opinion in …, 2017 - journals.lww.com
Looking closer at acute respiratory distress syndrome: the r... : Current Opinion in Critical Care
Looking closer at acute respiratory distress syndrome: the role of advanced imaging techniques …
Looking closer at acute respiratory distress syndrome: the role of advanced imaging techniques …
Unstable inflation causing injury. Insight from prone position and paired computed tomography scans
Rationale: It remains unclear how prone positioning improves survival in acute respiratory
distress syndrome. Using serial computed tomography (CT), we previously reported that …
distress syndrome. Using serial computed tomography (CT), we previously reported that …
Mechanical ventilation lessons learned from alveolar micromechanics
M Kollisch-Singule, J Satalin, SJ Blair… - Frontiers in …, 2020 - frontiersin.org
Morbidity and mortality associated with lung injury remains disappointingly unchanged over
the last two decades, in part due to the current reliance on lung macro-parameters set on the …
the last two decades, in part due to the current reliance on lung macro-parameters set on the …
A hybrid multibreath wash‐in wash‐out lung function quantification scheme in human subjects using hyperpolarized 3He MRI for simultaneous assessment of specific …
H Hamedani, S Kadlecek, Y Xin… - Magnetic resonance …, 2017 - Wiley Online Library
Purpose To present a method for simultaneous acquisition of alveolar oxygen tension
(PAO2), specific ventilation (SV), and apparent diffusion coefficient (ADC) of hyperpolarized …
(PAO2), specific ventilation (SV), and apparent diffusion coefficient (ADC) of hyperpolarized …
Global and regional heterogeneity of lung aeration in neonates with different respiratory disorders: a physiological, observational study
B Loi, V Sartorius, L Vivalda, A Fardi, G Regiroli… - …, 2024 - pubs.asahq.org
Background. Aeration heterogeneity affects lung stress and influences outcomes in adults
with acute respiratory distress syndrome (ARDS). We hypothesize that aeration …
with acute respiratory distress syndrome (ARDS). We hypothesize that aeration …