Therapeutic implications of targeting pyroptosis in Cardiac-related etiology of heart failure
O Habimana, OM Salami, J Peng, GH Yi - Biochemical pharmacology, 2022 - Elsevier
Heart failure remains a considerable clinical and public health problem, it is the dominant
cause of death from cardiovascular diseases, besides, cardiovascular diseases are one of …
cause of death from cardiovascular diseases, besides, cardiovascular diseases are one of …
[HTML][HTML] Intestinal permeability and gene expression after polyethylene and polyamide microplastic ingestion in Wistar rats
B Toto, A Refosco, M O'Keeffe, ØH Barkhald… - Toxicology Letters, 2022 - Elsevier
Microplastic particles are ubiquitous in the environment. However, little is known about their
uptake and effects in humans or mammalian model organisms. Here, we studied the effects …
uptake and effects in humans or mammalian model organisms. Here, we studied the effects …
Di (2‐ethylhexyl) phthalate and microplastics cause necroptosis and apoptosis in hepatocytes of mice by inducing oxidative stress
L Chen, M Qi, L Zhang, F Yu, D Tao… - Environmental …, 2023 - Wiley Online Library
Abstract Di (2‐ethylhexyl) phthalate (DEHP) is a plasticizer and an endocrine disruptor.
Microplastics (MPs) are pathogenic small plastic particles and abundant in the aqueous …
Microplastics (MPs) are pathogenic small plastic particles and abundant in the aqueous …
Microplastics and Oxidative Stress—Current Problems and Prospects
K Kadac-Czapska, J Ośko, E Knez, M Grembecka - Antioxidants, 2024 - mdpi.com
Microplastics (MPs) are plastic particles between 0.1 and 5000 µm in size that have attracted
considerable attention from the scientific community and the general public, as they threaten …
considerable attention from the scientific community and the general public, as they threaten …
[HTML][HTML] An Emerging Role of Micro-and Nanoplastics in Vascular Diseases
SE Lee, HK Yoon, DY Kim, TS Jeong, YS Park - Life, 2024 - mdpi.com
Vascular diseases are the leading causes of death worldwide, and they are attributable to
multiple pathologies, such as atherosclerosis, diabetes, and chronic obstructive pulmonary …
multiple pathologies, such as atherosclerosis, diabetes, and chronic obstructive pulmonary …
[HTML][HTML] Efficient extraction of small microplastic particles from rat feed and feces for quantification
To date, microplastic is ubiquitously encountered in the environment. Studies analyzing
microplastic in terrestrial ecosystems, including animal feces and feed, are few. Microplastic …
microplastic in terrestrial ecosystems, including animal feces and feed, are few. Microplastic …
LncRNA M iat knockdown protects against pirarubicin‐induced cardiotoxicity by targeting miRNA‐129‐1‐3p
P Huang, W Zhang, J Ji, J Ma, H Cheng… - Environmental …, 2023 - Wiley Online Library
Pirarubicin (THP) is a widely used antitumor drug in clinical practice, but its cardiotoxicity
limits its use. The aim of this study was to investigate the protective effect and mechanism of …
limits its use. The aim of this study was to investigate the protective effect and mechanism of …
[HTML][HTML] Toxicological effects of micro/nano-plastics on mouse/rat models: a systematic review and meta-analysis
W Liu, B Zhang, Q Yao, X Feng, T Shen… - Frontiers in Public …, 2023 - frontiersin.org
Micro/nano-plastics (MNPs) are considered a heterogeneous class of environmental
contaminants that cause multiple toxic effects on biological species. As the commonly used …
contaminants that cause multiple toxic effects on biological species. As the commonly used …
Natural swietenine attenuates diabetic nephropathy by regulating the NF‐κB/NLRP3/Caspase‐1 signaling pathways: In vivo and in vitro study
J Duan, L He, W Deng, M Lu, Y Zhai… - Environmental …, 2022 - Wiley Online Library
Abstract Swietenine (Swi), isolated from Swietenia macrophylla King ameliorates
inflammation and oxidative stress, and diabetic nephropathy has a close connection with …
inflammation and oxidative stress, and diabetic nephropathy has a close connection with …
The cardiovascular toxicity of polystyrene microplastics in rats: based on untargeted metabolomics analysis
Z Song, H Wu, X Fang, X Feng, L Zhou - Frontiers in Pharmacology, 2024 - frontiersin.org
Background Polystyrene microplastics (PS-MPs) exhibit multi-target, multi-dimensional,
chronic, and low toxicity to the cardiovascular system. They enter the bloodstream through …
chronic, and low toxicity to the cardiovascular system. They enter the bloodstream through …