Genomic rearrangements and the evolution of clusters of locally adaptive loci
S Yeaman - Proceedings of the National Academy of …, 2013 - National Acad Sciences
Numerous studies of ecological genetics have found that alleles contributing to local
adaptation sometimes cluster together, forming “genomic islands of divergence.” Divergence …
adaptation sometimes cluster together, forming “genomic islands of divergence.” Divergence …
[图书][B] Probability models for DNA sequence evolution
R Durrett, R Durrett - 2008 - Springer
Our basic question is: Given a collection of DNA sequences, what underlying forces are
responsible for the observed patterns of variability? To approach this question we introduce …
responsible for the observed patterns of variability? To approach this question we introduce …
The molecular and mathematical basis of Waddington's epigenetic landscape: A framework for post‐Darwinian biology?
S Huang - Bioessays, 2012 - Wiley Online Library
Abstract The Neo‐Darwinian concept of natural selection is plausible when one assumes a
straightforward causation of phenotype by genotype. However, such simple 1: 1 mapping …
straightforward causation of phenotype by genotype. However, such simple 1: 1 mapping …
Porcine models of digestive disease: the future of large animal translational research
There is increasing interest in nonrodent translational models for the study of human
disease. The pig, in particular, serves as a useful animal model for the study of …
disease. The pig, in particular, serves as a useful animal model for the study of …
[HTML][HTML] Epigenetic centromere propagation and the nature of CENP-a nucleosomes
BE Black, DW Cleveland - Cell, 2011 - cell.com
Centromeres direct chromosome inheritance, but in multicellular organisms their positions
on chromosomes are primarily specified epigenetically rather than by a DNA sequence. The …
on chromosomes are primarily specified epigenetically rather than by a DNA sequence. The …
Primate segmental duplications: crucibles of evolution, diversity and disease
JA Bailey, EE Eichler - Nature Reviews Genetics, 2006 - nature.com
Compared with other mammals, the genomes of humans and other primates show an
enrichment of large, interspersed segmental duplications (SDs) with high levels of sequence …
enrichment of large, interspersed segmental duplications (SDs) with high levels of sequence …
[图书][B] Combinatorics of genome rearrangements
G Fertin - 2009 - books.google.com
A comprehensive survey of a rapidly expanding field of combinatorial optimization,
mathematically oriented but offering biological explanations when required. From one cell to …
mathematically oriented but offering biological explanations when required. From one cell to …
Evolutionary stability of topologically associating domains is associated with conserved gene regulation
J Krefting, MA Andrade-Navarro, J Ibn-Salem - BMC biology, 2018 - Springer
Background The human genome is highly organized in the three-dimensional nucleus.
Chromosomes fold locally into topologically associating domains (TADs) defined by …
Chromosomes fold locally into topologically associating domains (TADs) defined by …
A high‐density linkage map enables a second‐generation collared flycatcher genome assembly and reveals the patterns of avian recombination rate variation and …
Detailed linkage and recombination rate maps are necessary to use the full potential of
genome sequencing and population genomic analyses. We used a custom collared …
genome sequencing and population genomic analyses. We used a custom collared …
Genomic legacy of the African cheetah, Acinonyx jubatus
Background Patterns of genetic and genomic variance are informative in inferring population
history for human, model species and endangered populations. Results Here the genome …
history for human, model species and endangered populations. Results Here the genome …