Plant-derived anticancer compounds as new perspectives in drug discovery and alternative therapy

CA Dehelean, I Marcovici, C Soica, M Mioc… - Molecules, 2021 - mdpi.com
Despite the recent advances in the field of chemically synthetized pharmaceutical agents,
nature remains the main supplier of bioactive molecules. The research of natural products is …

[HTML][HTML] Natural therapeutics and nutraceuticals for lung diseases: traditional significance, phytochemistry, and pharmacology

MM Rahman, S Bibi, MS Rahaman, F Rahman… - Biomedicine & …, 2022 - Elsevier
Background Lung diseases including chronic obstructive pulmonary disease (COPD),
infections like influenza, acute respiratory distress syndrome (ARDS), asthma and …

Anti‐inflammatory and anticancer activities of Naringenin‐loaded liquid crystalline nanoparticles in vitro

R Wadhwa, KR Paudel, LH Chin… - Journal of food …, 2021 - Wiley Online Library
In this study, we had developed Naringenin‐loaded liquid crystalline nanoparticles (LCNs)
and investigated the anti‐inflammatory and anticancer activities of Naringenin‐LCNs against …

Nutraceuticals: Transformation of conventional foods into health promoters/disease preventers and safety considerations

M AlAli, M Alqubaisy, MN Aljaafari, AO AlAli, L Baqais… - Molecules, 2021 - mdpi.com
Nutraceuticals are essential food constituents that provide nutritional benefits as well as
medicinal effects. The benefits of these foods are due to the presence of active compounds …

Resveratrol and vascular function

H Li, N Xia, S Hasselwander, A Daiber - International journal of molecular …, 2019 - mdpi.com
Resveratrol increases the production of nitric oxide (NO) in endothelial cells by upregulating
the expression of endothelial NO synthase (eNOS), stimulating eNOS enzymatic activity, and …

Adverse effects of cancer chemotherapy: Anything new to improve tolerance and reduce sequelae?

K Nurgali, RT Jagoe, R Abalo - Frontiers in pharmacology, 2018 - frontiersin.org
The side-effects and long-term sequelae of anti-cancer chemotherapy remain a major
source of concern for both patients and clinicians despite the improved efficacy and …

[HTML][HTML] The role of natural antioxidants against reactive oxygen species produced by cadmium toxicity: a review

V Unsal, T Dalkıran, M Çiçek… - Advanced pharmaceutical …, 2020 - ncbi.nlm.nih.gov
Cadmium (Cd) is a significant ecotoxic heavy metal that adversely affects all biological
processes of humans, animals and plants. Exposure to acute and chronic Cd damages …

Curcumin mediates anticancer effects by modulating multiple cell signaling pathways

AB Kunnumakkara, D Bordoloi, C Harsha… - Clinical …, 2017 - portlandpress.com
Curcumin, a component of a spice native to India, was first isolated in 1815 by Vogel and
Pelletier from the rhizomes of Curcuma longa (turmeric) and, subsequently, the chemical …

Long non-coding RNAs are emerging targets of phytochemicals for cancer and other chronic diseases

S Mishra, SS Verma, V Rai, N Awasthee… - Cellular and Molecular …, 2019 - Springer
The long non-coding RNAs (lncRNAs) are the crucial regulators of human chronic diseases.
Therefore, approaches such as antisense oligonucleotides, RNAi technology, and small …

Upsides and downsides of reactive oxygen species for cancer: the roles of reactive oxygen species in tumorigenesis, prevention, and therapy

SC Gupta, D Hevia, S Patchva, B Park… - Antioxidants & redox …, 2012 - liebertpub.com
Significance: Extensive research during the last quarter century has revealed that reactive
oxygen species (ROS) produced in the body, primarily by the mitochondria, play a major role …