Frontotemporal lobar degeneration (FTLD) is one of the most common causes of early-onset
dementia and presents with early social–emotional–behavioural and/or language changes …

Eukaryotic cells release different types of extracellular vesicles (EVs) including exosomes,
ectosomes, and microvesicles. Exosomes are nanovesicles, 30–200 nm in diameter, that …

Amyotrophic lateral sclerosis (ALS) and frontotemporal dementia (FTD) are two related
currently incurable neurodegenerative diseases. ALS is characterized by degeneration of …

Frontotemporal dementia (FTD) is a neurodegenerative disease of growing interest, since it
accounts for up to 10% of middle-age-onset dementias and entails a social, economic, and …

Introduction A systematic review and meta-analysis was performed regarding the diagnostic
performance of neurofilament light chain (NfL) in CSF and blood. Methods A database …

Background and Objectives To determine how fully automated Elecsys CSF immunoassays
for β-amyloid (Aβ) and tau biomarkers and an ultrasensitive Simoa assay for neurofilament …

Summary Background Neurofilament light chain (NfL) is a promising blood biomarker in
genetic frontotemporal dementia, with elevated concentrations in symptomatic carriers of …

The frontotemporal dementia (FTD) spectrum of neurodegenerative disorders includes a
heterogeneous group of conditions. However, following on from a series of important …

Objective To determine the association of serum neurofilament light chain (NfL) with
functional deterioration and brain atrophy during follow-up of patients with behavioral variant …

The diagnostic value of neurofilament light chain protein in neurodegenerative dementia
diseases is still controversial. A systematic literature search was performed to identify …