In recent years, three-dimensional (3D) bioprinting has been widely utilized as a novel
manufacturing technique by more and more researchers to construct various tissue …

Abstract Three-dimensional (3D) cell cultures have emerged as valuable tools in cancer
research, offering significant advantages over traditional two-dimensional (2D) cell culture …

Biomaterial templates play a critical role in establishing and bioinstructing three-dimensional
cellular growth, proliferation and spatial morphogenetic processes that culminate in the …

For effective translation of research from tissue engineering and regenerative medicine
domains, the cell‐instructive extracellular matrix (ECM) of specific tissues must be accurately …

Metabolic dysfunction-associated steatohepatitis (MASH) is the progressed version of
metabolic dysfunction-associated steatotic liver disease (MASLD) characterized by …

Background The extracellular matrix (ECM) is a three-dimensional network of proteins that
encases and supports cells within a tissue and promotes physiological and pathological …

During fibrosis,(myo) fibroblasts deposit large amounts of extracellular matrix proteins,
thereby replacing healthy functional tissue. In liver fibrosis, this leads to the loss of …

Hepatocellular carcinoma, the most common primary liver cancer and a leading cause of
death, is a difficult disease to treat due to its heterogeneous nature. Traditional models, such …

Malignancies of epithelial tissues, called carcinomas, account for the majority of cancer
cases. Much cancer research has focused on genetic alterations and their relation to …

Tissue engineering has emerged as an indispensable tool for the reconstruction of organ-
specific environments. Organ-derived extracellular matrices (ECM) and, especially …