Peptide-based nanovaccines in the treatment of cervical cancer: a review of recent advances

J Zhang, J Fan, M Skwarczynski… - International Journal …, 2022 - Taylor & Francis
Persistent infection with high-risk human papillomaviruses (HPVs), such as HPV-16 and
HPV-18, can induce cervical cancer in humans. The disease carries high morbidity and …

[HTML][HTML] The translation elongation factor eEF2 is a novel tumor‑associated antigen overexpressed in various types of cancers

Y Oji, N Tatsumi, M Fukuda… - International …, 2014 - spandidos-publications.com
Recent studies have shown that cancer immunotherapy could be a promising therapeutic
approach for the treatment of cancer. In the present study, to identify novel tumor-associated …

[HTML][HTML] A conserved E7-derived cytotoxic T lymphocyte epitope expressed on human papillomavirus 16-transformed HLA-A2+ epithelial cancers

AB Riemer, DB Keskin, G Zhang, M Handley… - Journal of Biological …, 2010 - ASBMB
Human Papillomavirus 16 (HPV-16) has been identified as the causative agent of 50% of
cervical cancers and many other HPV-associated tumors. The transforming potential/tumor …

A novel multi-epitope vaccine of HPV16 E5E6E7 oncoprotein delivered by HBc VLPs induced efficient prophylactic and therapeutic antitumor immunity in tumor mice …

W Qi, L Qingfeng, Z Jing, Z Maolin, Z Zhihui, D Wangqi… - Vaccine, 2022 - Elsevier
Human papilloma virus type 16 (HPV16) is the most prevalent etiologic agent associated
with cervical cancer, and its early proteins E5, E6 and E7 play important roles in cervical …

[HTML][HTML] Design, immune responses and anti-tumor potential of an HPV16 E6E7 multi-epitope vaccine

LMF de Oliveira, MG Morale, AAM Chaves… - Plos one, 2015 - journals.plos.org
Cervical cancer is a common type of cancer among women worldwide and infection with
high-risk human papillomavirus (HPVs) types represents the major risk factor for the …

Human papillomavirus vaccine: State of the art and future perspectives

D Panatto, D Amicizia, NL Bragazzi, E Rizzitelli… - Advances in protein …, 2015 - Elsevier
Human Papillomavirus (HPV) is a widely distributed and common virus, that causes benign
lesions (such as warts and papillomas) but, if not cleared, can lead to malignant lesions as …

HPV-16 E6 and E7 protein T cell epitopes prediction analysis based on distributions of HLA-A loci across populations: an in silico approach

Y Yao, W Huang, X Yang, W Sun, X Liu, W Cun, Y Ma - Vaccine, 2013 - Elsevier
Human papillomavirus type 16 (HPV-16) is the most prevalent virus in human cervical
cancers, as it is present in more than half of all cases. Many studies have found continued …

[HTML][HTML] Potential usage of proteasome inhibitor bortezomib (Velcade, PS-341) in the treatment of metastatic melanoma: basic and clinical aspects

MA Shahshahan, MN Beckley… - American journal of …, 2011 - ncbi.nlm.nih.gov
Protein degradation by proteasome is essential to the regulation of important cellular
functions including cell cycle progression, proliferation, differentiation and apoptosis …

[HTML][HTML] A comprehensive in silico analysis for identification of therapeutic epitopes in HPV16, 18, 31 and 45 oncoproteins

HA Panahi, A Bolhassani, G Javadi… - PloS one, 2018 - journals.plos.org
Human papillomaviruses (HPVs) are a group of circular double-stranded DNA viruses,
showing severe tropism to mucosal tissues. A subset of HPVs, especially HPV16 and 18, are …

[HTML][HTML] ARTEMIS: a novel mass-spec platform for HLA-restricted self and disease-associated peptide discovery

KAK Finton, MY Brusniak, LA Jones, C Lin… - Frontiers in …, 2021 - frontiersin.org
Conventional immunoprecipitation/mass spectroscopy identification of HLA-restricted
peptides remains the purview of specializing laboratories, due to the complexity of the …