[HTML][HTML] Microbiota in health and diseases

K Hou, ZX Wu, XY Chen, JQ Wang, D Zhang… - Signal transduction and …, 2022 - nature.com
The role of microbiota in health and diseases is being highlighted by numerous studies
since its discovery. Depending on the localized regions, microbiota can be classified into …

Local and systemic mechanisms linking periodontal disease and inflammatory comorbidities

G Hajishengallis, T Chavakis - Nature Reviews Immunology, 2021 - nature.com
Periodontitis, a major inflammatory disease of the oral mucosa, is epidemiologically
associated with other chronic inflammation-driven disorders, including cardio-metabolic …

[HTML][HTML] Periodontal disease: the good, the bad, and the unknown

LM Sedghi, M Bacino, YL Kapila - Frontiers in cellular and infection …, 2021 - frontiersin.org
Periodontal disease is classically characterized by progressive destruction of the soft and
hard tissues of the periodontal complex, mediated by an interplay between dysbiotic …

Interconnection of periodontal disease and comorbidities: Evidence, mechanisms, and implications

G Hajishengallis - Periodontology 2000, 2022 - Wiley Online Library
Periodontitis, a microbiome‐driven inflammatory disease of the tooth‐attachment apparatus,
is epidemiologically linked with other disorders, including cardio‐metabolic, cognitive …

Association between periodontitis and severity of COVID‐19 infection: A case–control study

N Marouf, W Cai, KN Said, H Daas… - Journal of clinical …, 2021 - Wiley Online Library
Aim COVID‐19 is associated with an exacerbated inflammatory response that can result in
fatal outcomes. Systemic inflammation is also a main characteristic of periodontitis …

Periodontal inflammation and systemic diseases: an overview

M Martínez-García, E Hernández-Lemus - Frontiers in physiology, 2021 - frontiersin.org
Periodontitis is a common inflammatory disease of infectious origins that often evolves into a
chronic condition. Aside from its importance as a stomatologic ailment, chronic periodontitis …

[HTML][HTML] Maladaptive innate immune training of myelopoiesis links inflammatory comorbidities

X Li, H Wang, X Yu, G Saha, L Kalafati, C Ioannidis… - Cell, 2022 - cell.com
Bone marrow (BM)-mediated trained innate immunity (TII) is a state of heightened immune
responsiveness of hematopoietic stem and progenitor cells (HSPC) and their myeloid …

Association between periodontal diseases and cardiovascular diseases, diabetes and respiratory diseases: Consensus report of the Joint Workshop by the European …

D Herrera, M Sanz, L Shapira, C Brotons… - Journal of clinical …, 2023 - Wiley Online Library
Aim To explore the implications for dentists and family doctors of the association between
periodontal and systemic diseases and the role of dentists and family doctors in managing …

Periodontitis and cardiovascular diseases: Consensus report

M Sanz, A Marco del Castillo, S Jepsen… - Journal of clinical …, 2020 - Wiley Online Library
Abstract Background In Europe cardiovascular disease (CVD) is responsible for 3.9 million
deaths (45% of deaths), being ischaemic heart disease, stroke, hypertension (leading to …

[HTML][HTML] The oralome and its dysbiosis: New insights into oral microbiome-host interactions

A Radaic, YL Kapila - Computational and structural biotechnology journal, 2021 - Elsevier
The oralome is the summary of the dynamic interactions orchestrated between the
ecological community of oral microorganisms (comprised of up to approximately 1000 …