[HTML][HTML] Oral absorption of peptides and nanoparticles across the human intestine: Opportunities, limitations and studies in human tissues

P Lundquist, P Artursson - Advanced drug delivery reviews, 2016 - Elsevier
In this contribution, we review the molecular and physiological barriers to oral delivery of
peptides and nanoparticles. We discuss the opportunities and predictivity of various in vitro …

Mucus-inspired dynamic hydrogels: Synthesis and future perspectives

R Bej, R Haag - Journal of the American Chemical Society, 2022 - ACS Publications
Mucus hydrogels at biointerfaces are crucial for protecting against foreign pathogens and for
the biological functions of the underlying cells. Since mucus can bind to and host both …

Bacterial hopping and trapping in porous media

T Bhattacharjee, SS Datta - Nature communications, 2019 - nature.com
Diverse processes—eg bioremediation, biofertilization, and microbial drug delivery—rely on
bacterial migration in disordered, three-dimensional (3D) porous media. However, how pore …

Mucus models to evaluate the diffusion of drugs and particles

JY Lock, TL Carlson, RL Carrier - Advanced drug delivery reviews, 2018 - Elsevier
Mucus is a complex hydrogel that acts as a natural barrier to drug delivery at different
mucosal surfaces including the respiratory, gastrointestinal, and vaginal tracts. To elucidate …

Extracellular-matrix-mediated osmotic pressure drives Vibrio cholerae biofilm expansion and cheater exclusion

J Yan, CD Nadell, HA Stone, NS Wingreen… - Nature …, 2017 - nature.com
Biofilms, surface-attached communities of bacteria encased in an extracellular matrix, are a
major mode of bacterial life. How the material properties of the matrix contribute to biofilm …

Gut biofilms: Bacteroides as model symbionts to study biofilm formation by intestinal anaerobes

N Béchon, JM Ghigo - FEMS microbiology reviews, 2022 - academic.oup.com
Bacterial biofilms are communities of adhering bacteria that express distinct properties
compared to their free-living counterparts, including increased antibiotic tolerance and …

Assessing and managing environmental hazards of polymers: historical development, science advances and policy options

KJ Groh, HPH Arp, M MacLeod, Z Wang - … Science: Processes & …, 2023 - pubs.rsc.org
Polymers are the main constituents of many materials and products in our modern world.
However, their environmental safety is not assessed with the same level of detail as done for …

Confinement and activity regulate bacterial motion in porous media

T Bhattacharjee, SS Datta - Soft matter, 2019 - pubs.rsc.org
Understanding how bacteria move in porous media is critical to applications in healthcare,
agriculture, environmental remediation, and chemical sensing. Recent work has …

A biophysical threshold for biofilm formation

JA Moore-Ott, S Chiu, DB Amchin, T Bhattacharjee… - Elife, 2022 - elifesciences.org
Bacteria are ubiquitous in our daily lives, either as motile planktonic cells or as immobilized
surface-attached biofilms. These different phenotypic states play key roles in agriculture …

Active dynamics of linear chains and rings in porous media

L Theeyancheri, S Chaki, T Bhattacharjee… - The Journal of …, 2023 - pubs.aip.org
To understand the dynamical and conformational properties of deformable active agents in
porous media, we computationally investigate the dynamics of linear chains and rings made …