Activational and effort-related aspects of motivation: neural mechanisms and implications for psychopathology
JD Salamone, SE Yohn, L López-Cruz, N San Miguel… - Brain, 2016 - academic.oup.com
Motivation has been defined as the process that allows organisms to regulate their internal
and external environment, and control the probability, proximity and availability of stimuli. As …
and external environment, and control the probability, proximity and availability of stimuli. As …
The neurobiology of activational aspects of motivation: exertion of effort, effort-based decision making, and the role of dopamine
JD Salamone, M Correa - Annual Review of Psychology, 2024 - annualreviews.org
Motivational processes are complex and multifaceted, with both directional and activational
aspects. Behavioral activation and exertion of effort are functions that enable organisms to …
aspects. Behavioral activation and exertion of effort are functions that enable organisms to …
Mechanisms of the psychostimulant effects of caffeine: implications for substance use disorders
S Ferré - Psychopharmacology, 2016 - Springer
Background The psychostimulant properties of caffeine are reviewed and compared with
those of prototypical psychostimulants able to cause substance use disorders (SUD) …
those of prototypical psychostimulants able to cause substance use disorders (SUD) …
Brain mechanisms underlying apathy
The past few decades have seen growing interest in the neuropsychiatric syndrome of
apathy, conceptualised as a loss of motivation manifesting as a reduction of goal-directed …
apathy, conceptualised as a loss of motivation manifesting as a reduction of goal-directed …
Mesolimbic dopamine and the regulation of motivated behavior
It has been known for some time that nucleus accumbens dopamine (DA) is involved in
aspects of motivation, but theoretical approaches to understanding the functions of DA have …
aspects of motivation, but theoretical approaches to understanding the functions of DA have …
[HTML][HTML] Dopamine, effort-based choice, and behavioral economics: basic and translational research
Operant behavior is not only regulated by factors related to the quality or quantity of
reinforcement, but also by the work requirements inherent in performing instrumental …
reinforcement, but also by the work requirements inherent in performing instrumental …
[HTML][HTML] Accumbens dopamine D2 receptors increase motivation by decreasing inhibitory transmission to the ventral pallidum
Abstract Dopamine D2 receptors (D2Rs) in the nucleus accumbens (NAc) regulate
motivated behavior, but the underlying neurobiological mechanisms remain unresolved …
motivated behavior, but the underlying neurobiological mechanisms remain unresolved …
Distinct effects of apathy and dopamine on effort-based decision-making in Parkinson's disease
Effort-based decision-making is a cognitive process crucial to normal motivated behaviour.
Apathy is a common and disabling complication of Parkinson's disease, but its aetiology …
Apathy is a common and disabling complication of Parkinson's disease, but its aetiology …
[HTML][HTML] Optogenetic self-stimulation in the nucleus accumbens: D1 reward versus D2 ambivalence
The nucleus accumbens (NAc) contains multiple subpopulations of medium spiny neurons
(MSNs). One subpopulation expresses D1-type dopamine receptors, another expresses D2 …
(MSNs). One subpopulation expresses D1-type dopamine receptors, another expresses D2 …
The psychopharmacology of effort-related decision making: dopamine, adenosine, and insights into the neurochemistry of motivation
Effort-based decision making is studied using tasks that offer choices between high-effort
options leading to more highly valued reinforcers versus low-effort/low-reward options …
options leading to more highly valued reinforcers versus low-effort/low-reward options …