Dissociable contributions of dorsal and ventral striatal regions on a rodent cost/benefit decision-making task requiring cognitive effort

MM Silveira, M Tremblay, CA Winstanley - Neuropharmacology, 2018 - Elsevier
Cognitive effort is a ubiquitous process, yet surprisingly little is known about the brain
mechanisms responsible for evaluating it. Here, we utilize the rat Cognitive Effort Task …

Impact of a history of caloric restriction and a frustration stress manipulation on binge-like eating behavior in female rats: preclinical results

MV Micioni Di Bonaventura… - Animal models of eating …, 2021 - Springer
Medications, at present, play a limited role on eating disorders. Currently, only two drugs
were approved by the Food and Drug Administration, fluoxetine and lisdexamfetamine …

Murine genetic variance in muscarinic cholinergic receptor antagonism of sucrose and saccharin solution intakes in three inbred mouse strains

F Bourie, K Olsson, B Iskhakov, A Buras… - Pharmacology …, 2017 - Elsevier
Nutritive (eg, sucrose) and non-nutritive (eg, saccharin) sweeteners stimulate intake in
inbred mouse strains. BALB/c, SWR and C57BL/6 mice differ in the ability of dopamine (DA) …

Dopaminergic activity mediates pups' over male preference of postpartum estrous rats

M Ferreño, N Uriarte, MJ Zuluaga, A Ferreira… - Physiology & …, 2018 - Elsevier
Pups have greater incentive value than males for rats during the postpartum estrus (PPE); a
period when females are both maternally and sexually motivated. Mesolimbic dopaminergic …

Muscarinic and nicotinic cholinergic receptor antagonists differentially mediate acquisition of fructose-conditioned flavor preference and quinine-conditioned flavor …

FM Rotella, K Olsson, V Vig, I Yenko, J Pagirsky… - … of Learning and …, 2015 - Elsevier
Rats display both conditioned flavor preference (CFP) for fructose, and conditioned flavor
avoidance (CFA) following sweet adulteration with quinine. Previous pharmacological …

The monoamine-oxidase B inhibitor deprenyl increases selection of high-effort activity in rats tested on a progressive ratio/chow feeding choice procedure …

SE Yohn, S Reynolds, G Tripodi, M Correa… - Behavioural brain …, 2018 - Elsevier
Motivated behaviors often are characterized by a high degree of behavioral activation and
work output, and organisms frequently make effort-related decisions based upon cost/benefit …

Neurobiology of effort and the role of mesolimbic dopamine

JD Salamone, M Correa - Recent developments in neuroscience …, 2016 - emerald.com
Classical definitions of motivation typically involve two main components: direction and
activation. Motivated behavior is directed toward or away from particular stimuli (ie …

Task-dependent effects of SKF83959 on operant behaviors associated with distinct changes of CaMKII signaling in striatal subareas

PP Liu, CC Chao, RM Liao - International Journal of …, 2021 - academic.oup.com
Background SKF83959, an atypical dopamine (DA) D1 receptor agonist, has been used to
test the functions of DA-related receptor complexes in vitro, but little is known about its …

Neural representation and modulation of volitional motivation in response to escalating efforts

L Zhang, C Liu, X Zhou, H Zhou, S Luo… - The Journal of …, 2023 - Wiley Online Library
Task‐dependent volitional control of the selected neural activity in the cortex is critical to
neuroprosthetic learning to achieve reliable and robust control of the external device. The …

Effect of streptozotocin-induced diabetes on performance on a progressive ratio schedule

L Valencia-Torres, CM Bradshaw, A Bouzas… - …, 2014 - Springer
Rationale It has been suggested that streptozotocin (STZ)-induced diabetes causes a
motivational deficit in rodents. However, some of the evidence adduced in support of this …