[HTML][HTML] Aging, bone marrow and next-generation sequencing (NGS): Recent advances and future perspectives

P Ganguly, B Toghill, S Pathak - International Journal of Molecular …, 2021 - mdpi.com
The aging of bone marrow (BM) remains a very imperative and alluring subject, with an ever-
increasing interest among fellow scientists. A considerable amount of progress has been …

[HTML][HTML] Measuring cell-to-cell expression variability in single-cell RNA-sequencing data: a comparative analysis and applications to B cell aging

H Zheng, J Vijg, AT Fard, JC Mar - Genome biology, 2023 - Springer
Background Single-cell RNA-sequencing (scRNA-seq) technologies enable the capture of
gene expression heterogeneity and consequently facilitate the study of cell-to-cell variability …

[HTML][HTML] Integration of osteoclastogenesis through addition of PBMCs in human osteochondral explants cultured ex vivo

EEA Cramer, BWM de Wildt, JGE Hendriks, K Ito… - Bone, 2024 - Elsevier
The preservation of tissue specific cells in their native 3D extracellular matrix in bone
explants provides a unique platform to study remodeling. Thus far, studies involving bone …

Mesenchymal stem cells (MSCs) from the mouse bone marrow show differential expression of interferon regulatory factors IRF-1 and IRF-2

JK Chaudhary, N Ahamad, PC Rath - Molecular Biology Reports, 2024 - Springer
Background Interferon regulatory factors (IRF-1 and IRF-2) are transcription factors widely
implicated in various cellular processes, including regulation of inflammatory responses to …

[HTML][HTML] Cancer Uses the Common Morphogenesis Source of the Host

AN Shoutko - Open Journal of Biophysics, 2020 - scirp.org
Trophic properties of hematopoietic stem cells can influence the malignant growth
alternatively to immune control. The annual growth of the body mass by age in adult …

[PDF][PDF] The Lifespan Hormesis Phenomenon in a Population Does Not Make It's Healthier

AN Shoutko, LP Ekimova - Challenges in Disease and Health …, 2021 - researchgate.net
Recently, radiation hormesis has been considered a form of useful cancer therapy when
total-body irradiation (TBI) is delivered to a cumulative dose of 1.5 Gy at about 0.1 Gy/day …

[引用][C] Statistical approaches to investigate cellular heterogeneity and stability in single-cell transcriptomic data

H Zheng - 2023 - espace.library.uq.edu.au
Modelling the heterogeneity and stability in single-cell transcriptomics data accelerates the
understanding of regulatory mechanisms in different biological processes and conditions …