[HTML][HTML] Melatonin as modulator for sulfur and nitrogen mustard-induced inflammation, oxidative stress and DNA damage: Molecular therapeutics

E Ramos, E Gil-Martín, C De Los Ríos, J Egea… - Antioxidants, 2023 - mdpi.com
Sulfur and nitrogen mustards, bis (2-chloroethyl) sulfide and tertiary bis (2-chloroethyl)
amines, respectively, are vesicant warfare agents with alkylating activity. Moreover …

[HTML][HTML] Three classes of antioxidant defense systems and the development of postmenopausal osteoporosis

K Yang, F Cao, Y Xue, L Tao, Y Zhu - Frontiers in Physiology, 2022 - frontiersin.org
Osteoporosis is a common bone imbalance disease that threatens the health of
postmenopausal women. Estrogen deficiency accelerates the aging of women. Oxidative …

Immunolocalization of melatonin receptors in bovine ovarian follicles and in vitro effects of melatonin on growth, viability and gene expression in secondary follicles

L Paulino, PAA Barroso, BR Silva, LG Barroso… - Domestic Animal …, 2022 - Elsevier
This study aims to investigate the (1) expression of melatonin receptors types 1A/B
(MTNR1A/B) in bovine ovaries and (2) the in vitro effects of melatonin on secondary follicle …

Rapamycin encourages the maintenance of mitochondrial dynamic balance and mitophagy activity for improving developmental competence of blastocysts in porcine …

HJ Park, GD Heo, SG Yang… - Molecular Reproduction …, 2023 - Wiley Online Library
Rapamycin induces autophagosome formation and activity during oocyte maturation,
improved fertilization ability of matured oocytes, and early embryonic developmental …

[HTML][HTML] Melatonin improves the quality of rotenone-exposed mouse oocytes through association with histone modifications

X Wang, H Li, H Mu, S Zhang, Y Li, X Han… - Ecotoxicology and …, 2023 - Elsevier
Rotenone, an insecticide that inhibits mitochondrial complex I and generates oxidative
stress, is responsible for neurological disorders and affects the female reproductive system …

[HTML][HTML] Stabilization of F-actin cytoskeleton by paclitaxel improves the blastocyst developmental competence through P38 MAPK activity in porcine embryos

SY Joe, SG Yang, JH Lee, HJ Park, DB Koo - Biomedicines, 2022 - mdpi.com
Changes in F-actin distribution and cortical F-actin morphology are important for blastocyst
developmental competence during embryogenesis. However, the effect of paclitaxel as a …

Melatonin improves meiosis maturation against diazinon exposure in mouse oocytes

Y Gai, MY Zhang, PY Ji, RJ You, ZJ Ge, W Shen… - Life Sciences, 2022 - Elsevier
Aims Organophosphorus pesticide diazinon (DZN) has adverse effects on animals and
humans by direct contact or the spread of food chain. The antioxidant melatonin has …

Mito-TEMPO protects preimplantation porcine embryos against mitochondrial fission-driven apoptosis through DRP1/PINK1-mediated mitophagy

SG Yang, JW Bae, HJ Park, DB Koo - Life Sciences, 2023 - Elsevier
Abstract Aims Mdivi-1 (Md-1) is a well-known inhibitor of mitochondrial fission and
mitophagy. The mitochondrial superoxide scavenger Mito-TEMPO (MT) exerts positive …