The mechanism of multiple organ dysfunction syndrome in patients with COVID‐19

W Zhao, H Li, J Li, B Xu, J Xu - Journal of medical virology, 2022 - Wiley Online Library
In late 2019, an outbreak of coronavirus disease 2019 (COVID‐19) arose, caused by severe
acute respiratory syndrome coronavirus type 2 (SARS‐CoV‐2). This disease rapidly became …

[HTML][HTML] ACE2 down-regulation may act as a transient molecular disease causing RAAS dysregulation and tissue damage in the microcirculatory environment among …

SG Ramos, BA da Cruz Rattis, G Ottaviani… - The American journal of …, 2021 - Elsevier
Abstract SARS-CoV-2 (severe acute respiratory syndrome coronavirus 2), the etiological
agent of COVID-19 (coronavirus disease 2019) and the cause of the current pandemic …

[HTML][HTML] SARS-CoV-2 spike protein disrupts blood–brain barrier integrity via RhoA activation

BJ DeOre, KA Tran, AM Andrews, SH Ramirez… - Journal of Neuroimmune …, 2021 - Springer
The SARS-CoV-2 spike protein has been shown to disrupt blood–brain barrier (BBB)
function, but its pathogenic mechanism of action is unknown. Whether angiotensin …

[HTML][HTML] The association of airborne particulate matter and benzo [a] pyrene with the clinical course of COVID-19 in patients hospitalized in Poland

P Rzymski, B Poniedziałek, J Rosińska… - Environmental …, 2022 - Elsevier
Air pollution can adversely affect the immune response and increase the severity of the viral
disease. The present study aimed to explore the relationship between symptomatology …

[HTML][HTML] Role of SARS-COV-2 and ACE2 in the pathophysiology of peripheral vascular diseases

H Tanzadehpanah, E Lotfian, A Avan, S Saki… - Biomedicine & …, 2023 - Elsevier
The occurrence of a novel coronavirus known as severe acute respiratory syndrome-
coronavirus-2 (SARS-CoV-2), created a serious challenge worldwide. SARS-CoV-2 has …

[HTML][HTML] The age-dependent decline of the extracellular thiol-disulfide balance and its role in SARS-CoV-2 infection

D Giustarini, A Santucci, D Bartolini, F Galli, R Rossi - Redox Biology, 2021 - Elsevier
Abstract SARS–CoV-2 (COVID-19) infection can cause a severe respiratory distress
syndrome. The risk of severe manifestations and mortality characteristically increase in the …

The classical and potential novel healthy functions of rice bran protein and its hydrolysates

Y Yu, GK Gaine, L Zhou, J Zhang… - Critical reviews in food …, 2022 - Taylor & Francis
Rice bran protein (RBP) is a plant protein obtained from rice bran, a byproduct produced
during rice milling process. It has been proved to be a high quality protein due to containing …

Counter-regulatory renin-angiotensin system in hypertension: Review and update in the era of COVID-19 pandemic

H Chen, J Peng, T Wang, J Wen, S Chen… - Biochemical …, 2023 - Elsevier
Cardiovascular disease is the major cause of mortality and disability, with hypertension
being the most prevalent risk factor. Excessive activation of the renin-angiotensin system …

Screening S protein–ACE2 blockers from natural products: strategies and advances in the discovery of potential inhibitors of COVID-19

H Liu, X Liu, X Yuan, C Xu, F Wang, J Lin, R Xu… - European Journal of …, 2021 - Elsevier
Abstract The Coronavirus disease, 2019 (COVID-19) is caused by severe acute respiratory
syndrome Coronavirus 2 (SARS-CoV-2), which poses a major threat to human life and …

[HTML][HTML] Integrating heterogeneous data to facilitate COVID-19 drug repurposing

LP Santamaría, MD Uzquiano, EU Carro… - Drug Discovery …, 2022 - Elsevier
In the COVID-19 pandemic, drug repositioning has presented itself as an alternative to the
time-consuming process of generating new drugs. This review describes a drug repurposing …