The skin is one of the most essential organs in the human body, interacting with the external
environment and shielding the body from diseases and excessive water loss. Thus, the loss …

At least half of all amputations occur in people with diabetes, most commonly because of an
infected diabetic foot ulcer. A thorough understanding of the causes and management of …

Background Large area skin trauma has always been a great challenge for both patients
and clinicians. Exosomes originating from human adipose-derived mesenchymal stem cells …

Acute wound healing is an orderly process of four overlapping events: haemostasis,
inflammation, proliferation and remodelling. A drug delivery system with a temporal control …

In recent years, as living standards have continued to improve, the number of diabetes
patients in China, along with the incidence of complications associated with the disease, has …

Tissue engineering is a promising strategy to repair spinal cord injury (SCI). However, a
bioscaffold with mechanical properties that match those of the pathological spinal cord …

The inertness of synthetic polymer materials and the insufficient mechanical strength of
reprocessed decellularized extracellular matrix (dECM) limited their promotive efforts on …

Macrophages are versatile and plastic effector cells of the immune system, and contribute to
diverse immune functions including pathogen or apoptotic cell removal, inflammatory …

Non-healing wound, with limited treatment options, remains a prevalent complication of
diabetes mellitus. The underlying causes wherein include oxidative stress injury, bacterial …

There are currently over 80 biomaterials derived from autologous, allogeneic, synthetic and
xenogeneic sources, or a combination of any or all these types of materials, available for soft …