The NLRP3 inflammasome pathway: a review of mechanisms and inhibitors for the treatment of inflammatory diseases
The NLRP3 inflammasome is a multiprotein complex that plays a pivotal role in regulating
the innate immune system and inflammatory signaling. Upon activation by PAMPs and …
the innate immune system and inflammatory signaling. Upon activation by PAMPs and …
Health benefits of quercetin in age-related diseases
Polyphenols are the known group of phytochemicals that essentially consists of phenolic
rings. These are the plant product present in varied fruits and vegetables. These secondary …
rings. These are the plant product present in varied fruits and vegetables. These secondary …
Senolytics dasatinib and quercetin in idiopathic pulmonary fibrosis: results of a phase I, single-blind, single-center, randomized, placebo-controlled pilot trial on …
Background Idiopathic pulmonary fibrosis (IPF) is an age-related, chronic, irreversible
fibrotic lung disease. IPF is associated with increased senescent cells burden, which may be …
fibrotic lung disease. IPF is associated with increased senescent cells burden, which may be …
Mitochondrial adaptation in cancer drug resistance: prevalence, mechanisms, and management
Drug resistance represents a major obstacle in cancer management, and the mechanisms
underlying stress adaptation of cancer cells in response to therapy-induced hostile …
underlying stress adaptation of cancer cells in response to therapy-induced hostile …
Plant-derived anticancer compounds as new perspectives in drug discovery and alternative therapy
CA Dehelean, I Marcovici, C Soica, M Mioc… - Molecules, 2021 - mdpi.com
Despite the recent advances in the field of chemically synthetized pharmaceutical agents,
nature remains the main supplier of bioactive molecules. The research of natural products is …
nature remains the main supplier of bioactive molecules. The research of natural products is …
Potential mechanisms of quercetin in cancer prevention: focus on cellular and molecular targets
Over the past few years, the cancer-related disease has had a high mortality rate and
incidence worldwide, despite clinical advances in cancer treatment. The drugs used for …
incidence worldwide, despite clinical advances in cancer treatment. The drugs used for …
Senolytics and senomorphics: Natural and synthetic therapeutics in the treatment of aging and chronic diseases
SM Lagoumtzi, N Chondrogianni - Free Radical Biology and Medicine, 2021 - Elsevier
Cellular senescence is a heterogeneous process guided by genetic, epigenetic and
environmental factors, characterizing many types of somatic cells. It has been suggested as …
environmental factors, characterizing many types of somatic cells. It has been suggested as …
Dietary polyphenols in chemoprevention and synergistic effect in cancer: Clinical evidences and molecular mechanisms of action
Background Epidemiological studies has revealed that a diet rich in fruits and vegetables
could lower the risk of certain cancers. In this setting, natural polyphenols are potent …
could lower the risk of certain cancers. In this setting, natural polyphenols are potent …
Novel Carboxymethyl Cellulose-Based Hydrogel with Core–Shell Fe3O4@SiO2 Nanoparticles for Quercetin Delivery
M Mahdi Eshaghi, M Pourmadadi, A Rahdar… - Materials, 2022 - mdpi.com
A nanocomposite composed of carboxymethyl cellulose (CMC) and core–shell
nanoparticles of Fe3O4@ SiO2 was prepared as a pH-responsive nanocarrier for quercetin …
nanoparticles of Fe3O4@ SiO2 was prepared as a pH-responsive nanocarrier for quercetin …
[HTML][HTML] Novel extraction, rapid assessment and bioavailability improvement of quercetin: A review
Quercetin (QUR) have got the attention of scientific society frequently due to their wide range
of potential applications. QUR has been the focal point for research in various fields …
of potential applications. QUR has been the focal point for research in various fields …