[HTML][HTML] Therapeutic drug monitoring is a feasible tool to personalize drug administration in neonates using new techniques: an overview on the pharmacokinetics and …

DU De Rose, S Cairoli, M Dionisi, A Santisi… - International journal of …, 2020 - mdpi.com
Therapeutic drug monitoring (TDM) should be adopted in all neonatal intensive care units
(NICUs), where the most preterm and fragile babies are hospitalized and treated with many …

[HTML][HTML] Rational use of antibiotics in neonates: still in search of tailored tools

J van den Anker, K Allegaert - Healthcare, 2019 - mdpi.com
Rational medicine use in neonates implies the prescription and administration of age-
appropriate drug formulations, selecting the most efficacious and safe dose, all based on …

Towards understanding global patterns of antimicrobial use and resistance in neonatal sepsis: insights from the NeoAMR network

G Li, JA Bielicki, ASMNU Ahmed, MS Islam… - Archives of disease in …, 2020 - adc.bmj.com
Objective To gain an understanding of the variation in available resources and clinical
practices between neonatal units (NNUs) in the low-income and middle-income country …

The Neonatal and Paediatric Pharmacokinetics of Antimicrobials study (NAPPA): investigating amoxicillin, benzylpenicillin, flucloxacillin and piperacillin …

CIS Barker, K Kipper, DO Lonsdale… - Journal of …, 2023 - academic.oup.com
Background Pharmacokinetic (PK) data underlying paediatric penicillin dosing remain
limited, especially in critical care. Objectives The primary objective of the Neonatal and …

Dose optimization of β-lactam antibiotics in children: from population pharmacokinetics to individualized therapy

P Ngougni Pokem, D Vanneste… - Expert Opinion on …, 2024 - Taylor & Francis
Introduction β-Lactams are the most widely used antibiotics in children. Their optimal dosing
is essential to maximize their efficacy, while minimizing the risk for toxicity and the further …

Neonates are not just little children and need more finesse in dosing of antibiotics

K Allegaert, J van den Anker - Acta Clinica Belgica, 2019 - Taylor & Francis
Objectives: Neonates are not just little children. They need more finesse in decisions on
when to treat, which antibiotics to use and how to dose these antibiotics. Methods …

[HTML][HTML] β-lactam precision dosing in critically ill children: Current state and knowledge gaps

S Tang Girdwood, K Pavia, K Paice… - Frontiers in …, 2022 - frontiersin.org
There has been emerging interest in implementing therapeutic drug monitoring and model-
informed precision dosing of β-lactam antibiotics in critically ill patients, including children …

Validated HPLC method for ceftriaxone from dried blood spots for pharmacokinetic studies and therapeutic drug monitoring in neonatal population

BB Chaudhari, BH Devadiga, S Matcha, LES Lewis… - Bioanalysis, 2023 - Taylor & Francis
Background: Pharmacokinetic evaluation is essential for the precise dosing of ceftriaxone in
neonates. There is a need for developing a sensitive, affordable and convenient analytical …

[HTML][HTML] Antimicrobianos en neonatología. Parte I: Recomendaciones de dosificaciones basadas, en la más reciente evidencia en recién nacidos Comité Consultivo …

A Sandoval, M Aravena, F Cofré, L Delpiano… - Revista chilena de …, 2020 - SciELO Chile
Los antimicrobianos son los medicamentos más utilizados en los neonatos durante su
primer mes de vida cuando se encuentran en unidades neonatales, principalmente por el …

[PDF][PDF] Versión in press ID 813

A Sandoval, M Aravena, F Cofré, L Delpiano… - pdfs.semanticscholar.org
Los antimicrobianos son los medicamentos más utilizados en los neonatos durante su
primer mes de vida cuando se encuentran en unidades neonatales, principalmente por el …