The influence of lung deposition on clinical response

JN Pritchard - Journal of Aerosol Medicine, 2001 - liebertpub.com
Delivery of more drug to the lung may appear to be a desirable goal in the treatment of
asthma and chronic obstructive pulmonary disease, since only 10 to 15% of a drug dose …

A review on the safety and efficacy of inhaled corticosteroids in the management of asthma

Q Ye, XO He, A D'Urzo - Pulmonary Therapy, 2017 - Springer
Asthma is a chronic inflammatory disease characterized by symptoms of cough, dyspnea,
chest tightness, and wheeze. Inhaled corticosteroids (ICS) have been recommended as …

Multicentre randomised placebo-controlled trial of inhaled fluticasone propionate in patients with chronic obstructive pulmonary disease

PL Paggiaro, R Dahle, I Bakran, L Frith, K Hollingworth… - The Lancet, 1998 - thelancet.com
Background The efficacy of inhaled corticosteroids in the treatment of chronic obstructive
pulmonary disease (COPD) remains controversial because of a lack of placebo-controlled …

Lung deposition of hydrofluoroalkane-134a beclomethasone is greater than that of chlorofluorocarbon fluticasone and chlorofluorocarbon beclomethasone: a cross …

CL Leach, PJ Davidson, BE Hasselquist, RJ Boudreau - Chest, 2002 - Elsevier
Study objectives To compare the lung deposition of radiolabeled hydrofluoroalkane-134a
beclomethasone dipropionate (HFA-BDP) with chlorofluorocarbon fluticasone propionate …

Combined salmeterol 50 μ g and fluticasone propionate 250 μ g in the Diskus device for the treatment of asthma

G Shapiro, W LUMRY, J Wolfe, J Given… - American journal of …, 2000 - atsjournals.org
Three hundred forty-nine patients with asthma previously treated with medium doses of
inhaled corticosteroids during a 2-wk, single-blind, run-in period were randomized to …

Adrenal suppression, evaluated by a low dose adrenocorticotropin test, and growth in asthmatic children treated with inhaled steroids

S Kannisto, M Korppi, K Remes… - The Journal of Clinical …, 2000 - academic.oup.com
The aim of the present study was to evaluate the prevalence of adrenal suppression and
growth retardation in children using moderate doses of budesonide or fluticasone …

[PDF][PDF] Inhaled and nasal corticosteroids: safety aspects

G Passalacqua, M Albano, GW Canonica, C Bachert… - Allergy, 2000 - academia.edu
Introduction The commercially available inhaled corticosteroids (ICS) for asthma treatment
are beclomethasone dipropionate (BDP), budesonide (BUD), flunisolide (FLU), fluticasone …

Fluticasone versus beclomethasone or budesonide for chronic asthma in adults and children

NP Adams, TJ Lasserson, CJ Cates… - Cochrane Database of …, 2007 - cochranelibrary.com
Background Beclomethasone dipropionate (BDP) and budesonide (BUD) are commonly
prescribed inhaled corticosteroids for the treatment of asthma. Fluticasone propionate (FP) is …

Advair: combination treatment with fluticasone propionate/salmeterol in the treatment of asthma

HS Nelson - Journal of allergy and clinical immunology, 2001 - Elsevier
Several classes of medications are available for the treatment of asthma, and often they
must be taken concurrently to achieve asthma control. Based on the understanding of …

Dose-response relationship of inhaled budesonide in adult asthma: a meta-analysis

M Masoli, S Holt, M Weatherall… - European Respiratory …, 2004 - Eur Respiratory Soc
The aim of this study was to examine the dose-response relationship of inhaled budesonide
in adolescents and adults with asthma. A meta-analysis was carried out on placebo …