Soluble N-ethylmaleimide-sensitive factor attachment protein receptors (SNAREs) are a
family of small conserved eukaryotic proteins that mediate membrane fusion between …

The recent proliferation of cryo-electron tomography (cryo-ET) techniques has led to the cryo-
ET resolution revolution. Meanwhile, significant efforts have been made to improve the …

HIV-1 Env mediates viral entry into host cells and is the sole target for neutralizing
antibodies. However, Env structure and organization in its native virion context has eluded …

Influenza A virus causes millions of severe cases of disease during annual epidemics. The
most abundant protein in influenza virions is matrix protein 1 (M1), which mediates virus …

Attachment to and fusion with cell membranes are two major steps in the replication cycle of
many human viruses. We focus on these steps for three enveloped viruses, ie, HIV-1, IAVs …

Myomerger is a muscle-specific membrane protein involved in formation of multinucleated
muscle cells by mediating the transition from the early hemifusion stage to complete fusion …

Among the current five Variants of Concern, infections caused by SARS-CoV-2 B. 1.617. 2
(Delta) variant are often associated with the greatest severity. Despite recent advances on …

To enter a cell and establish infection, HIV must first fuse its lipid envelope with the host cell
plasma membrane. Whereas the process of HIV membrane fusion can be tracked by …

Highlights•Cryo-electron tomography reconstructions of paramyxovirus particles have
yielded novel insight into virion assembly and organization.•Newcastle disease virus matrix …

Membrane fusion is fundamental to biological processes as diverse as membrane trafficking
or viral infection. Proteins catalyzing membrane fusion need to overcome energy barriers to …