Preclinical noninvasive imaging can be an indispensable tool for studying animal models of
disease. In vivo imaging to assess anatomical, functional, and molecular features requires …

Lung ventilation was mapped in seven healthy male Sprague‐Dawley rats (433±24 g) using
hyperpolarized 129Xe magnetic resonance imaging (MRI) at 3.0 T, and validated with …

The current study focuses on the use of scanning laser optical tomography (SLOT) in
imaging of the mouse lung ex vivo. SLOT is a highly efficient fluorescence microscopy …

Lung diseases, including pneumonia and asthma, are among the most prevalent human
disorders, and murine models have been established to investigate their pathobiology and …

We present a new lung imaging technique based on endoscopic confocal fluorescence
microscopy (ECFM), which is a new method that is able to provide cellular and structural …

The pathophysiology of acute lung injury (ALI) is well characterized, but its real-time
assessment at bedside remains a challenge. When patients do not improve after 1 wk …

Available imaging systems for use in preclinical toxicology studies increasingly show utility
as important tools in the toxicologic pathologist's armamentarium, permit longitudinal …

Background: In vivo videomicroscopy has been used for years to visualize subpleural alveoli
in animal studies. This has led to a better understanding of alveolar physiology. We tested …

Inappropriate lung inflammatory response following oxidant and toxicant exposure can lead
to abnormal repair and disease pathogenesis, including fibrosis. Thus early detection of …

Lung ventilation was mapped in five healthy Brown Norway rats (210–377 g) using both
hyperpolarized 3He MRI and Xe‐enhanced computed tomography (Xe‐CT) under similar …