The mechanisms of HBV-induced hepatocellular carcinoma

Y Jiang, Q Han, H Zhao, J Zhang - Journal of hepatocellular …, 2021 - Taylor & Francis
Hepatocellular carcinoma (HCC) is a common malignancy, and the hepatitis B virus (HBV) is
its major pathogenic factor. Over the past decades, it has been confirmed that HBV infection …

[HTML][HTML] Validation and promise of a TCR mimic antibody for cancer immunotherapy of hepatocellular carcinoma

C Liu, H Liu, M Dasgupta, LM Hellman, X Zhang… - Scientific Reports, 2022 - nature.com
Monoclonal antibodies are at the vanguard of the most promising cancer treatments.
Whereas traditional therapeutic antibodies have been limited to extracellular antigens, T cell …

[HTML][HTML] A systematic review of T cell epitopes defined from the proteome of hepatitis B virus

Y Wu, Y Ding, C Shen - Vaccines, 2022 - mdpi.com
Hepatitis B virus (HBV) infection remains a worldwide health problem and no eradicative
therapy is currently available. Host T cell immune responses have crucial influences on the …

[HTML][HTML] Conservation and variability of hepatitis B core at different chronic hepatitis stages

M Yll, MF Cortese, M Guerrero-Murillo… - World Journal of …, 2020 - ncbi.nlm.nih.gov
BACKGROUND Since it is currently not possible to eradicate hepatitis B virus (HBV)
infection with existing treatments, research continues to uncover new therapeutic strategies …

Mooring Stone-Like Arg114 Pulls Diverse Bulged Peptides: First Insight into African Swine Fever Virus-Derived T Cell Epitopes Presented by Swine Major …

C Yue, W Xiang, X Huang, Y Sun, J Xiao, K Liu… - Journal of …, 2022 - Am Soc Microbiol
African swine fever virus (ASFV) is the causative agent of African swine fever (ASF), which is
a devastating pig disease threatening the global pork industry. However, currently, no …

Altered gut microbiota is associated with the formation of occult hepatitis B virus infection

B Liu, H Yang, Q Liao, M Wang, J Huang… - Microbiology …, 2024 - Am Soc Microbiol
Hepatitis B virus (HBV), a common blood transmission pathogen worldwide, can lead to viral
hepatitis, cirrhosis, liver cancer, and other liver diseases. In particular, occult hepatitis B virus …

[HTML][HTML] Hepatitis B virus-specific cellular immunity contributes to the outcome of occult hepatitis B virus infection

W Zhang, S Luo, T Li, M Wang, J Huang… - Frontiers in …, 2022 - frontiersin.org
There is little known of immunologic factors leading to the occurrence of occult HBV infection
(OBI). Specific cellular immune response to hepatitis B virus (HBV) core/pol peptides was …

[HTML][HTML] Insights into the interplay between KIR gene frequencies and chronic HBV infection in Burkina Faso

PA Sorgho, JJ Martinson, FW Djigma… - … of Hematology and …, 2018 - ncbi.nlm.nih.gov
Methods Chronic HBV carriers and healthy patients were selected for this study. The viral
load for HBV were performed, and SSP-PCR was used to characterize the frequencies of …

HDV evolution—will viral resistance be an issue in HDV infection?

D Tabernero, MF Cortese, M Buti… - Current opinion in …, 2018 - Elsevier
Highlights•Hepatitis delta virus has a high genetic diversity and limited antiviral
targets.•Interferon α is the only antiviral treatment available; new options are in trial.•Most …

The genetic variability of hepatitis B virus subgenotype F1b precore/core gene is related to the outcome of the acute infection

J Trinks, S Marciano, I Esposito, A Franco, MF Mascardi… - Virus research, 2020 - Elsevier
Aim To assess the association of viral and host genetic variability with the outcome of acute
infection with hepatitis B virus subgenotype F1b (HBV/F1b). Methods The cohort consisted of …