Kidney disease patient representation in trials of combination therapy with VEGF-signaling pathway inhibitors and immune checkpoint inhibitors: a systematic review

BMP Elyan, S Rankin, R Jones, NN Lang… - Kidney …, 2023 - kidneymedicinejournal.org
Combination therapy with vascular endothelial growth factor signaling pathway inhibitors
(VSPIs) and immune checkpoint inhibitors (ICIs) has led to major improvements in cancer …

Assessment of Glomerular Filtration Rate in Patients with Cancer: A Statement from the American Society of Onco-Nephrology

A Kitchlu, VTCE Silva, S Anand, J Kala… - Clinical Journal of the …, 2024 - journals.lww.com
Accurate assessment of glomerular filtration rate (GFR) is crucial to guiding drug eligibility,
dosing of systemic therapy, and minimizing the risks of both undertreatment and toxicity in …

Time to abandon renalism: patients with kidney diseases deserve more

JP Gaut - Clinical Journal of the American Society of Nephrology, 2023 - journals.lww.com
Conscious exclusion of patients with kidney disease from drug trials is a commonly accepted
practice. 1 This must change. In the United States, 37 million adults, 15% of the population …

Inclusion of participants with CKD and other kidney-related considerations during clinical drug development: landscape analysis of anticancer agents approved from …

MA Butrovich, AC Reaves, J Heyward… - Clinical Journal of the …, 2023 - journals.lww.com
Background The US Food and Drug Administration has prioritized efforts to expand
availability of therapies, including anticancer agents, for patients with CKD. US Food and …

Association between renal dysfunction and outcomes of lung cancer: A systematic review and meta‑analysis

H Qian, S Li, Z Hu - Oncology Letters, 2024 - spandidos-publications.com
Renal insufficiency and/or chronic kidney disease are common comorbidities in patients with
lung cancer, potentially affecting their prognosis. The aim of the present study was to assess …

Assessment of GFR in Patients with Cancer Part 2: Anticancer Therapies–Perspectives from the ASON

A Kitchlu, VTCE Silva, S Anand, J Kala… - Clinical Journal of the …, 2024 - journals.lww.com
In Part 2 of this statement from the American Society of Onco-Nephrology, we address
issues related to glomerular filtration rate (GFR) and anticancer therapies, including …

Comparison of different sustained‐release opioids and acute respiratory conditions in patients with cancer and chronic kidney disease

S Mitsuboshi, S Imai, H Kizaki… - … : The Journal of Human …, 2024 - Wiley Online Library
Abstract Study Objective Few data are available on the association between the use of
oxycodone in patients with chronic kidney disease (CKD) and acute respiratory conditions …

[HTML][HTML] Tepotinib in a patient with advanced non-small cell lung cancer harboring MET exon 14 skipping undergoing concomitant hemodialysis for renal failure: A …

M Kleemiss, CE Müller, M Schneider, R Strotmann… - Clinical Lung Cancer, 2024 - Elsevier
Lung cancer is the leading cause of cancer-related death worldwide, 1 with non-small cell
lung cancer (NSCLC) accounting for> 80–85% of cases. 2 In patients with lung cancer, renal …

Call for Greater Adoption of Recommended Standards during Cancer Drug Development to Improve Cancer Care with CKD

UD Patel - Clinical Journal of the American Society of Nephrology, 2023 - journals.lww.com
As the second leading cause of death in the United States, 1 improving the care of people
who develop cancer is a national priority. Outcomes for people with cancer have been …

Cancer Treatment in CKD: Time to Move Beyond Renalism

JR Berger, MA Vazquez - Kidney360, 2023 - journals.lww.com
because they had kidney disease. Limiting patient access to best treatment options solely
because of the presence of kidney disease is a form of renalism. This term was first used …