Understanding nanoparticle endocytosis to improve targeting strategies in nanomedicine

MS de Almeida, E Susnik, B Drasler… - Chemical society …, 2021 - pubs.rsc.org
Nanoparticles (NPs) have attracted considerable attention in various fields, such as
cosmetics, the food industry, material design, and nanomedicine. In particular, the fast …

Yersinia pestis--etiologic agent of plague

RD Perry, JD Fetherston - Clinical microbiology reviews, 1997 - Am Soc Microbiol
Plague is a widespread zoonotic disease that is caused by Yersinia pestis and has had
devastating effects on the human population throughout history. Disappearance of the …

Type III protein secretion systems in bacterial pathogens of animals and plants

CJ Hueck - Microbiology and molecular biology reviews, 1998 - Am Soc Microbiol
Various gram-negative animal and plant pathogens use a novel, sec-independent protein
secretion system as a basic virulence mechanism. It is becoming increasingly clear that …

The Virulence Plasmid of Yersinia, an Antihost Genome

GR Cornelis, A Boland, AP Boyd… - Microbiology and …, 1998 - Am Soc Microbiol
The 70-kb virulence plasmid enables Yersinia spp.(Yersinia pestis, Y. pseudotuberculosis,
and Y. enterocolitica) to survive and multiply in the lymphoid tissues of their host. It encodes …

Target cell contact triggers expression and polarized transfer of Yersinia YopE cytotoxin into mammalian cells.

R Rosqvist, KE Magnusson, H Wolf‐Watz - The EMBO journal, 1994 - embopress.org
Pathogenic bacteria of the species Yersinia, including Yersinia pestis, block phagocytosis by
macrophages. This process involves the YopE protein, which induces disruption of the host …

[HTML][HTML] Yersinia type III secretion: send in the effectors

GR Cornelis - The Journal of cell biology, 2002 - ncbi.nlm.nih.gov
Abstract Pathogenic Yersinia spp (Yersinia pestis, Yersinia pseudotuberculosis, and
Yersinia enterocolitica) have evolved an exquisite method for delivering powerful effectors …

The Yersinia Ysc–Yop 'Type III' weaponry

GR Cornelis - Nature Reviews Molecular Cell Biology, 2002 - nature.com
Abstract'Type III secretion'—the mechanism by which some pathogenic bacteria inject
proteins straight into the cytosol of eukaryotic cells to'anaesthetize'or'enslave'them—was …

The Yersinia Yop virulon: a bacterial system for subverting eukaryotic cells

GR Cornelis, H Wolf‐Watz - Molecular microbiology, 1997 - Wiley Online Library
The Yop virulon enables Yersinia spp.(Y. pestis, Y. pseudotuberculosis and Y.
enterocolitica) to survive and multiply in the lymphoid tissues of their host. It is an integrated …

[PDF][PDF] The Yersinia virulence factor YopM hijacks host kinases to inhibit type III effector-triggered activation of the pyrin inflammasome

LK Chung, YH Park, Y Zheng, IE Brodsky, P Hearing… - Cell host & …, 2016 - cell.com
Pathogenic Yersinia, including Y. pestis, the agent of plague in humans, and Y.
pseudotuberculosis, the related enteric pathogen, deliver virulence effectors into host cells …

[PDF][PDF] The Yersinia virulence effector YopM binds caspase-1 to arrest inflammasome assembly and processing

CN LaRock, BT Cookson - Cell host & microbe, 2012 - cell.com
Inflammasome assembly activates caspase-1 and initiates the inflammatory cell death
program pyroptosis, which is protective against numerous pathogens. Consequently …