[HTML][HTML] Pseudomonas aeruginosa: an antibiotic resilient pathogen with environmental origin

P Laborda, F Sanz-García, S Hernando-Amado… - Current Opinion in …, 2021 - Elsevier
Highlights•P. aeruginosa is opportunistic pathogen with an environmental origin.•P.
aeruginosa presents low susceptibility to currently used antibiotics.•P. aeruginosa displays a …

Impact of multidrug resistance on the virulence and fitness of Pseudomonas aeruginosa: a microbiological and clinical perspective

E Sendra, A Fernández-Muñoz, L Zamorano, A Oliver… - Infection, 2024 - Springer
Pseudomonas aeruginosa is one of the most common nosocomial pathogens and part of the
top emergent species associated with antimicrobial resistance that has become one of the …

Whole-genome sequencing reveals high-risk clones of Pseudomonas aeruginosa in Guangdong, China

Y Zhao, D Chen, B Ji, X Zhang, M Anbo… - Frontiers in …, 2023 - frontiersin.org
The ever-increasing prevalence of infections produced by multidrug-resistant or extensively
drug-resistant Pseudomonas aeruginosa is commonly linked to a limited number of aptly …

Direct RNA nanopore sequencing of Pseudomonas aeruginosa clone C transcriptomes

MM Pust, CF Davenport, L Wiehlmann… - Journal of …, 2022 - Am Soc Microbiol
The transcriptomes of Pseudomonas aeruginosa clone C isolates NN2 and SG17M during
the mid-exponential and early stationary phases of planktonic growth were evaluated by …

Phylogroup-specific variation shapes the clustering of antimicrobial resistance genes and defence systems across regions of genome plasticity in Pseudomonas …

J Botelho, L Tüffers, J Fuss, F Buchholz, C Utpatel… - …, 2023 - thelancet.com
Background Pseudomonas aeruginosa is an opportunistic pathogen consisting of three
phylogroups (hereafter named A, B, and C). Here, we assessed phylogroup-specific …

Evolution under low antibiotic concentrations: a risk for the selection of Pseudomonas aeruginosa multidrug‐resistant mutants in nature

F Sanz‐García, S Hernando‐Amado… - Environmental …, 2022 - Wiley Online Library
Antibiotic pollution of non‐clinical environments might have a relevant impact on human
health if resistant pathogens are selected. However, this potential risk is often overlooked …

In vitro activity of imipenem/relebactam against Pseudomonas aeruginosa isolates recovered from ICU patients in Spain and Portugal (SUPERIOR and STEP studies …

M Hernández-García, M García-Castillo… - Journal of …, 2022 - academic.oup.com
Objectives To study the in vitro activity of imipenem/relebactam and comparators and the
imipenem/relebactam resistance mechanisms in a Pseudomonas aeruginosa collection …

Perspectives on the Pseudomonas aeruginosa Type III Secretion System Effector ExoU and Its Subversion of the Host Innate Immune Response to Infection

KS Hardy, MH Tessmer, DW Frank, JP Audia - Toxins, 2021 - mdpi.com
Pseudomonas aeruginosa is an opportunistic, Gram-negative pathogen and an important
cause of hospital acquired infections, especially in immunocompromised patients. Highly …

Worldwide distribution and environmental origin of the Adelaide imipenemase (AIM-1), a potent carbapenemase in Pseudomonas aeruginosa

A Amsalu, SA Sapula, JJ Whittall… - Microbial …, 2021 - microbiologyresearch.org
Carbapenems are potent broad-spectrum β-lactam antibiotics reserved for the treatment of
serious infections caused by multidrug-resistant bacteria such as Pseudomonas aeruginosa …

Pseudomonas aeruginosa Pangenome: Core and Accessory Genes of a Highly Resourceful Opportunistic Pathogen

KZ Abram, SR Jun, Z Udaondo - Pseudomonas aeruginosa: Biology …, 2022 - Springer
In this chapter, we leverage a novel approach to assess the seamless population structure of
Pseudomonas aeruginosa, using the full repertoire of genomes sequenced to date …