Computational approach to combat COVID-19 infection: emerging tools for accelerating drug research
Background: The process of drug discovery and development is expensive, complex,
timeconsuming, and risky. There are different techniques involved in the process of drug …
timeconsuming, and risky. There are different techniques involved in the process of drug …
Application of computational and bioinformatics techniques in drug repurposing for effective development of potential drug candidate for the management of COVID …
CO Adetunji, OT Olugbemi, M Akram… - … Forensic Science and …, 2022 - taylorfrancis.com
The novel Coronavirus Disease-19 (COVID-19) outbreak has significantly affected different
human activities in the globalized world. Since the outbreak of the COVID-19 pandemic …
human activities in the globalized world. Since the outbreak of the COVID-19 pandemic …
DReAmocracy: A Method to Capitalise on Prior Drug Discovery Efforts to Highlight Candidate Drugs for Repurposing
In the area of drug research, several computational drug repurposing studies have
highlighted candidate repurposed drugs, as well as clinical trial studies that have tested/are …
highlighted candidate repurposed drugs, as well as clinical trial studies that have tested/are …
Leveraging distributed biomedical knowledge sources to discover novel uses for known drugs
F Womack, J McClelland, D Koslicki - bioRxiv, 2019 - biorxiv.org
Computational drug repurposing, also called drug repositioning, is a low cost, promising tool
for finding new uses for existing drugs. With the continued growth of repositories of …
for finding new uses for existing drugs. With the continued growth of repositories of …
[PDF][PDF] Drug repurposing: Recent advancements, challenges, and future therapeutics for cancer treatment
MI Danjuma, ME Entonu… - J Bacteriol Mycol Open …, 2022 - researchgate.net
Cancer has been a major public health concern, 1 being the second leading cause of death
globally, and is responsible for an estimated 9.9 million deaths in 2020, with a projection of …
globally, and is responsible for an estimated 9.9 million deaths in 2020, with a projection of …
Unlocking therapeutic potential: computational insights into TREM2 protein targeting with FDA-approved drugs for neurodegeneration
Neurodegenerative diseases such as Alzheimer's disease (AD) pose a significant global
health challenge that requires the exploration of innovative therapeutic strategies. Triggering …
health challenge that requires the exploration of innovative therapeutic strategies. Triggering …
Multi-data aspects of protein similarity with a learning technique to identify drug-disease associations
S Kitsiranuwat, A Suratanee, K Plaimas - Applied Sciences, 2021 - mdpi.com
Drug repositioning has been proposed to develop drugs for diseases. However, the
similarity in a single aspect may not be sufficient to reveal hidden information. Therefore, we …
similarity in a single aspect may not be sufficient to reveal hidden information. Therefore, we …
Discovery of new drug indications for COVID-19: A drug repurposing approach
Motivation The outbreak of coronavirus health issues caused by COVID-19 (SARS-CoV-2)
creates a global threat to public health. Therefore, there is a need for effective remedial …
creates a global threat to public health. Therefore, there is a need for effective remedial …
Computational approaches for development of anti-COVID-19 agents
Drug discovery is a complicated, laborious, and costly process that involves several
methods including random screening, molecular dynamics, computational techniques …
methods including random screening, molecular dynamics, computational techniques …
Comprehensive evaluation of collaborative filtering in drug repurposing
Drug development is known to be a costly and time-consuming process, which is prone to
high failure rates. Drug repurposing allows drug discovery to consider reusing approved …
high failure rates. Drug repurposing allows drug discovery to consider reusing approved …