Revisiting the dose constraints for head and neck OARs in the current era of IMRT

NP Brodin, WA Tomé - Oral oncology, 2018 - Elsevier
Head and neck cancer poses a particular challenge in radiation therapy, whilst being an
effective treatment modality it requires very high doses of radiation to provide effective …

Systematic review of normal tissue complication models relevant to standard fractionation radiation therapy of the head and neck region published after the QUANTEC …

NP Brodin, R Kabarriti, MK Garg, C Guha… - International Journal of …, 2018 - Elsevier
There has recently been an increasing interest in model-based evaluation and comparison
of different treatment options in radiation oncology studies. This is partly driven by the …

Intensity‐modulated proton therapy for nasopharyngeal carcinoma: decreased radiation dose to normal structures and encouraging clinical outcomes

GD Lewis, EB Holliday, E Kocak–Uzel… - Head & …, 2016 - Wiley Online Library
Background Intensity‐modulated proton therapy (IMPT) has the potential to spare dose to
organs at risk (OAR) when compared to intensity‐modulated radiotherapy (IMRT) while …

Head and neck cancer adaptive radiation therapy (ART): conceptual considerations for the informed clinician

J Heukelom, CD Fuller - Seminars in radiation oncology, 2019 - Elsevier
For nearly 2 decades, adaptive radiation therapy (ART) has been proposed as a method to
account for changes in head and neck tumor and normal tissue to enhance therapeutic …

[HTML][HTML] Incorporating spatial dose metrics in machine learning-based normal tissue complication probability (NTCP) models of severe acute dysphagia resulting from …

J Dean, K Wong, H Gay, L Welsh, AB Jones… - Clinical and translational …, 2018 - Elsevier
Severe acute dysphagia commonly results from head and neck radiotherapy (RT). A model
enabling prediction of severity of acute dysphagia for individual patients could guide clinical …

Systematic review and meta‐analysis of the impact of dosimetry to dysphagia and aspiration related structures

EK Charters, H Bogaardt… - Head & …, 2019 - Wiley Online Library
Background Technological advances in radiotherapy have allowed investigations into new
methods to spare healthy tissue in those treated for head and neck cancer. This systematic …

Dysphagia optimized radiotherapy to reduce swallowing dysfunction severity in patients undergoing treatment for head and neck cancer: a systematized scoping …

AR Hutchison, B Cartmill, LR Wall, EC Ward - Head & Neck, 2019 - Wiley Online Library
This study involved a systematized scoping review to coalesce current evidence on
dysphagia outcomes achieved through active sparing of the swallowing structures in …

[HTML][HTML] Enteral nutrition during radiotherapy for oropharyngeal cancers: prevalence and prognostic factors based on HPV status (a GETTEC study)

D Culié, R Schiappa, T Pace-Loscos… - Journal of Clinical …, 2023 - mdpi.com
Nutritional support during radiotherapy is crucial to tolerating and completing oropharyngeal
squamous cell carcinoma (OPSCC) treatment. The impact of HPV status on nutritional …

Influence of dosimetric and clinical criteria on the requirement of artificial nutrition during radiotherapy of head and neck cancer patients

C Matuschek, E Bölke, C Geigis, K Kammers… - Radiotherapy and …, 2016 - Elsevier
Purpose/objective (s) Intensification of radiotherapy and chemotherapy for head-and-neck
cancer (HNC) may lead to increased rates of long term dysphagia as a severe side effect …

Efficacy of Kanglaite against radiotherapy-induced mucositis in head and neck cancer, a phase II trial

ZP Liu, QY Song, CL Chu, SH Liu, YX Ren, J Chen… - Cancer …, 2022 - Elsevier
Purpose To explore the potential protective effect of Kanglaite injection against radiotherapy-
induced mucositis in patients with head and neck cancer. Patients and methods This was an …