Recombinant proteins (RP) are widely used as biopharmaceuticals, industrial enzymes, or
sustainable food source. Yeasts, with their ability to produce complex proteins through a …

Pichia pastoris, a methylotrophic yeast, is an established system for the production of
heterologous proteins, particularly biopharmaceuticals and industrial enzymes. To maximise …

During the past 15 years, the methylotrophic yeast Pichia pastoris has developed into a
highly successful system for the production of a variety of heterologous proteins. The …

Yeasts are widely used in production of recombinant proteins of medical or industrial
interest. For each individual product, the most suitable expression system has to be …

The methylotrophic yeast Pichia pastoris has been widely reported as a suitable expression
system for heterologous protein production. The use of different phenotypes under PAOX …

The patatin-like phospholipase domain containing 3 (PNPLA3, also called adiponutrin,
ADPN) is a membrane-bound protein highly expressed in the liver. The genetic variant …

Pichia pastoris has been used extensively and successfully to express recombinant
proteins. In this review, we summarize the elements required for expressing heterologous …

High-cell-density cultivation (HCDC) is required to improve microbial biomass and product
formation substantially. An overview of HCDC is given for microorganisms including …

The expression of heterologous proteins may exert severe stress on the host cells at
different levels. Depending on the specific features of the product, different steps may be rate …

Methylotrophic yeasts such as Candida boidinii, Hansenula polymorpha, Pichia methanolica
and Pichia pastoris are an emerging group of eukaryotic hosts for recombinant protein …