Age-associated chronic inflammation is characterized by unresolved and uncontrolled
inflammation with multivariable low-grade, chronic and systemic responses that exacerbate …

Obesity and associated chronic inflammation initiate a state of insulin resistance (IR). The
secretion of chemoattractants such as MCP-1 and MIF and of cytokines IL-6, TNF-α, and IL …

House dust mite (HDM) is one of the most common allergens worldwide. In this study, we
have addressed the involvement of IL-1 in the interaction between HDM and the innate …

Saturated fatty acid (SFA) high-fat diets (HFDs) enhance interleukin (IL)-1β–mediated
adipose inflammation and insulin resistance. However, the mechanisms by which different …

The proinflammatory cytokine interleukin-1β (IL-1β) plays a central role in the pathogenesis
and the course of inflammatory skin diseases, including psoriasis. Posttranscriptional …

Rosacea is a chronic relapsing inflammatory skin disease with high prevalence worldwide.
Recent research suggests that dysregulation of innate and adaptive immune pathways as …

Worldwide obesity rates have reached epidemic proportions and significantly contribute to
the growing prevalence of metabolic diseases. Chronic low-grade inflammation, a hallmark …

Exposure of the lungs to airborne toxicants from different sources in the environment may
lead to acute and chronic pulmonary or even systemic inflammation. Cigarette smoke is the …

OBJECTIVE High-fat diet (HFD)-induced adipose tissue inflammation is a critical feature of
diet-induced insulin resistance (IR); however, the contribution of interleukin-1 receptor I (IL …

Review of the activation of inflammasome processes IL-1β and IL-18, which synergize with
IL-23 to promote IL-17 production, by IL-17-secreting γδ T and Th17 cells. NLRs are …