Systemic sclerosis-associated interstitial lung disease

A Perelas, RM Silver, AV Arrossi… - The Lancet respiratory …, 2020 - thelancet.com
Systemic sclerosis is an autoimmune connective tissue disease, which is characterised by
immune dysregulation and progressive fibrosis that typically affects the skin, with variable …

Pathophysiology of systemic sclerosis: current understanding and new insights

M Cutolo, S Soldano, V Smith - Expert review of clinical …, 2019 - Taylor & Francis
ABSTRACT Introduction: Systemic sclerosis (SSc) is a complex autoimmune connective
tissue disease characterized by chronic and progressive tissue and organ fibrosis with …

Detection of microvascular changes in systemic sclerosis and other rheumatic diseases

M Cutolo, V Smith - Nature Reviews Rheumatology, 2021 - nature.com
Morphological and functional analysis of the microcirculation are objective outcome
measures that are recommended for use in the presence of clinical signs of altered …

[HTML][HTML] Nailfold capillaroscopy

V Smith, C Ickinger, E Hysa, M Snow, T Frech… - Best Practice & …, 2023 - Elsevier
Nailfold capillaroscopy is a safe and well-established method for the assessment of
structural alterations of the microcirculation. It is a crucial tool in the investigation and …

The pathogenesis, diagnosis and treatment of Raynaud phenomenon

AL Herrick - Nature Reviews Rheumatology, 2012 - nature.com
The past 10 years have seen the publication of results from several multicentre clinical trials
in primary and systemic sclerosis (SSc)-related Raynaud phenomenon. The publication of …

Managing rheumatic and musculoskeletal diseases—past, present and future

GR Burmester, JWJ Bijlsma, M Cutolo… - Nature Reviews …, 2017 - nature.com
Progress in rheumatology has been remarkable in the past 70 years, favourably affecting
quality of life for people with rheumatic and musculoskeletal diseases. Therapeutics have …

How to perform and interpret capillaroscopy

M Cutolo, A Sulli, V Smith - Best practice & research clinical rheumatology, 2013 - Elsevier
The essence of capillaroscopy is to examine, noninvasively and safely the morphology of
nailfold dermal papillary capillaries using a magnification system (microscopical lenses) …

Microvascular imaging: techniques and opportunities for clinical physiological measurements

J Allen, K Howell - Physiological measurement, 2014 - iopscience.iop.org
The microvasculature presents a particular challenge in physiological measurement
because the vessel structure is spatially inhomogeneous and perfusion can exhibit high …

[PDF][PDF] Nailfold videocapillaroscopic features and other clinical risk factors for digital ulcers in systemic sclerosis: a multicenter, prospective cohort study

M Cutolo, AL Herrick, O Distler, MO Becker… - Arthritis & …, 2016 - Wiley Online Library
Objective To identify nailfold videocapillaroscopic features and other clinical risk factors for
new digital ulcers (DUs) during a 6‐month period in patients with systemic sclerosis (SSc) …

Nailfold capillaroscopy in systemic sclerosis: data from the EULAR scleroderma trials and research (EUSTAR) database

F Ingegnoli, I Ardoino, P Boracchi, M Cutolo, P Airò… - Microvascular …, 2013 - Elsevier
Objective The aims of this study were to obtain cross-sectional data on capillaroscopy in an
international multi-center cohort of Systemic Sclerosis (SSc) and to investigate the frequency …