Rising rates of resistance to antimicrobial drugs among Enterobacteriaceae limit the choice
of reliably active forms of these drugs. We evaluated the evidence on fosfomycin as a …

Classification of urinary tract infections (UTI) is important for clinical decisions, research,
quality measurement and teaching. Current definitions of UTI are above all based on the …

Background: Urinary tract infections (UTIs) are among the most common infections in the
pediatric population. Over the last two decades, antibiotic resistance is increasing …

The aim of this prospective cohort study was to determine the risk factors for community-
acquired urinary tract infections (UTIs) caused by extended-spectrum β-lactamase (ESBL) …

Background Extended-spectrum β-lactamases (ESBLs) are an increasing challenge in the
treatment of urinary tract infections (UTIs), and also in the community. We aimed to …

OBJECTIVES: Extended-spectrum β-lactamase (ESBL)-producing Escherichia coli have
emerged as significant causes of community-onset disease. We sought to identify risk factors …

Background Urinary tract infection (UTI) caused by resistant bacteria is becoming more
prevalent. Few studies are available regarding community-onset UTIs caused by extended …

1. Executive summary Multi-drug-resistant (MDR) Gram-negative bacterial infections have
become prevalent in some European countries. Moreover, increased use of broad-spectrum …

Introduction Empirical therapy for the treatment of urinary tract infections should be tailored
to the current distribution and susceptibility of potential pathogens to ensure optimal …

Beta-lactam drugs, whose mechanism of action is inhibition of the last stage of bacterial cell
wall synthesis, are the largest family of antimicrobial agents and the most widely used in …