[HTML][HTML] Impact of inflammation on cytochromes P450 activity in pediatrics: a systematic review

C Lenoir, F Rodieux, JA Desmeules, V Rollason… - Clinical …, 2021 - Springer
Abstract Background and Objective Cytochromes P450 (CYP) are the major enzymes
involved in hepatic metabolism of drugs. Personalization of treatment in pediatrics is a major …

[HTML][HTML] Challenges and recommendations for the management of asthma in the Middle East and Africa

MO Zeitouni, MS Al-Moamary, ML Coussa… - Annals of thoracic …, 2022 - journals.lww.com
Clinical presentation of asthma is variable, and its diagnosis can be a major challenge in
routine health-care practice, especially in low-and-middle-income countries. The aim of …

[HTML][HTML] Prevalence of overweight and obesity and their impact on spirometry parameters in patients with asthma: a multicentre, retrospective study

AA Alqarni, AM Aldhahir, RA Siraj, JS Alqahtani… - Journal of clinical …, 2023 - mdpi.com
Introduction: Obesity is a common comorbidity in patients with asthma and has a significant
impact on health and prognoses. However, the extent to which overweight and obesity …

Graph convolutional neural network with multi-layer attention mechanism for predicting potential microbe-disease associations

L Wang, X Yang, L Kuang, Z Zhang… - Current …, 2023 - ingentaconnect.com
Background: Human microbial communities play an important role in some physiological
process of human beings. Nevertheless, the identification of microbe-disease associations …

Overprescription of short‐acting β2‐agonists among patients with asthma in Saudi Arabia: Results from the SABINA III cohort study

H Al‐Jahdali, S Wali, AS Albanna… - The Clinical …, 2022 - Wiley Online Library
Despite near‐universal health care and timely updates to treatment guidelines in Saudi
Arabia, asthma control remains suboptimal, warranting deeper exploration of its …

[HTML][HTML] Pulmonary outcomes of congenital diaphragmatic hernia patients based on defect size (CDH Study Group Stage)

H Emanuel, HV Breitschopf, MT Harting… - Translational …, 2023 - ncbi.nlm.nih.gov
Background Congenital diaphragmatic hernia (CDH) is associated with significant
pulmonary morbidity. Previous investigation has shown that postnatal inpatient morbidity is …

Assessment of the Current Practice of Managing Depression in Patients with Asthma in Saudi Arabia: Physicians' Views

RA Siraj, AM Alrajeh, AE Alhaykan… - Journal of Asthma …, 2023 - Taylor & Francis
Objective Depression is a common comorbidity in patients with asthma with a significant
impact on clinical management. However, little information is available about physicians' …

[HTML][HTML] Adverse drug reactions (ADRs) of montelukast in children

A Al-Shamrani, S Alharbi, S Kobeisy, SA AlKhater… - Children, 2022 - mdpi.com
Montelukast is a leukotriene receptor antagonist (LTRA) commonly prescribed for asthma,
allergic rhinitis and sleep-related breathing disorders. Recently, some studies have reported …

[HTML][HTML] Asthma medication adherence, control, and psychological symptoms: a cross-sectional study

AA Alqarni, AM Aldhahir, RA Siraj, JS Alqahtani… - BMC Pulmonary …, 2024 - Springer
Background Nonadherence to therapies and psychological disorders are associated with
poor asthma control. This study aims to assess the prevalence of anxiety and depressive …

Expert Consensus on Oral Corticosteroids Stewardship for the Treatment of Severe Asthma in the Middle East and Africa

M Al-Ahmad, A Al Zaabi, A Madkour, HA Alqaraghuli… - Respiratory …, 2024 - Elsevier
Abstract In the Middle East and Africa (MEA) region, overuse of oral corticosteroids (OCS) for
asthma management, both as burst and maintenance therapy, poses a significant challenge …