Epigenetic regulation in the tumor microenvironment: molecular mechanisms and therapeutic targets

J Yang, J Xu, W Wang, B Zhang, X Yu… - Signal transduction and …, 2023 - nature.com
Over decades, researchers have focused on the epigenetic control of DNA-templated
processes. Histone modification, DNA methylation, chromatin remodeling, RNA modification …

A methylation-and immune-related lncRNA signature to predict ovarian cancer outcome and uncover mechanisms of chemoresistance

L Chen, W Gao, L Lin, C Sha, T Li, Q Chen… - Journal of Ovarian …, 2023 - Springer
Tumor-associated lncRNAs regulated by epigenetic modification switches mediate immune
escape and chemoresistance in ovarian cancer (OC). However, the underlying mechanisms …

Emerging role of RNA modification and long noncoding RNA interaction in cancer

L Yang, L Tang, Q Min, H Tian, L Li, Y Zhao… - Cancer Gene …, 2024 - nature.com
RNA modification, especially N6-methyladenosine, 5-methylcytosine, and N7-
methylguanosine methylation, participates in the occurrence and progression of cancer …

Comprehensive assessment of base excision repair (BER)-related lncRNAs as prognostic and functional biomarkers in lung adenocarcinoma: implications for …

J Zhang, L Song, G Li, A Liang, X Cai, Y Huang… - Journal of Cancer …, 2023 - Springer
Background Lung adenocarcinoma (LUAD) is the most prevalent subtype of lung cancer,
and comprehending its molecular mechanisms is pivotal for advancing treatment efficacy …

Involvement of RNA methylation modification patterns mediated by m7G, m6A, m5C and m1A regulators in immune microenvironment regulation of Sjögren's …

Y Liu, J Zhu, L Ding - Cellular Signalling, 2023 - Elsevier
Keratoconjunctivitis is the most common complication of Sjögren's syndrome (SS). It has
always been a hot research topic due to its complex pathogenesis. A further understanding …

M7G-Related lncRNAs predict prognosis and regulate the immune microenvironment in lung squamous cell carcinoma

J Pan, Z Huang, H Lin, W Cheng, J Lai, J Li - BMC cancer, 2022 - Springer
Abstract Background N7-Methylguanosine (m7G) and long non-coding RNAs (lncRNAs)
have been widely studied in cancer and have been found to be useful for assessing tumor …

A novel prognostic signature based on N7-methylguanosine-related long non-coding RNAs in breast cancer

Z Huang, K Lou, H Liu - Frontiers in Genetics, 2022 - frontiersin.org
Long non-coding RNA (lncRNA) are closely associated with the occurrence and progression
of tumors. However, research on N7-methylguanosine (m7G)-related lncRNA in breast …

Comprehensive pan-cancer analysis of N7-methylguanosine regulators: Expression features and potential implications in prognosis and immunotherapy

W Wei, C Liu, C Wang, M Wang, W Jiang, Y Zhou… - Frontiers in …, 2022 - frontiersin.org
Although immunotherapy has made great strides in cancer therapy, its effectiveness varies
widely among individual patients as well as tumor types, and there is an urgent need to …

Prognostic potential of m7G-associated lncRNA signature in predicting bladder cancer response to immunotherapy and chemotherapy

D Li, R Wu, J Wang, D Feng, S Deng - Oncologie, 2023 - degruyter.com
Objectives The influence of N7-methylguanosine (m7G) on cancer prognosis and immune
response has been well-reported. However, the role of m7G-related long non-coding RNAs …

[HTML][HTML] Identification of N7-methylguanosine-related lncRNAs for the risk stratification of hepatocellular carcinoma

Y Li, K Zhao, R Wu, J Wang, Q Wang… - Journal of …, 2023 - ncbi.nlm.nih.gov
Background Hepatocellular carcinoma (HCC) is one of the most common malignancies in
the world. The N7-methylguanosine (m7G) modification is related to the biological …