Initiation and development of cancer depend on multiple factors that mutations in genes and
epigenetic level can be considered as important drivers. Epigenetic factors include a large …

Mitochondrial dysfunction arises from an inadequate number of mitochondria, an inability to
provide necessary substrates to mitochondria, or a dysfunction in their electron transport and …

Background: Acute myeloid leukemia (AML) is one of the most common malignant and
aggressive hematologic tumors, and its pathogenesis is associated with abnormal post …

Osteoarthritis (OA) is a common degenerative joint disorder, which involves articular
cartilage degeneration as well as joint inflammatory reactions. The recent studies have …

Oral cancer (OC) is a widely observed neoplasm on a global scale. Over time, there has
been an increase in both its fatality and incidence rates. Oral cancer metastasis is a complex …

In 2018 bladder cancer (urothelial carcinoma) was ranked twelfth concerning worldwide
diagnosis of malignancies. At the time point of diagnosis of bladder cancer, approximately …

Background & Aims Constipation is commonly associated with diabetes. Serotonin (5-HT),
produced predominantly by enterochromaffin (EC) cells via tryptophan hydroxylase 1 …

Oral cancer is the thirteenth most common cancer in the world, with India contributing to 33%
of the global burden. Lack of specific non-invasive markers, non-improvement in patient …

Polycystic ovary syndrome (PCOS) is the most common endocrine disorder among
reproductive-age women. Women with PCOS have a 2.7-fold increased risk for developing …

MicroRNAs (miRNAs) are a family of highly conserved, non-coding single-stranded RNAs
transcribed as~ 70 nucleotide precursors to an 18–22 nucleotide product. miRNAs can …