Astrocytes participate in information processing by releasing neuroactive substances termed
gliotransmitters, including ATP. Individual astrocytes come into contact with thousands of …

Despite significant advances in our understanding of the pathophysiology of multiple
sclerosis (MS), knowledge about contribution of individual ion channels to axonal …

Seaweeds have a naturally salty taste owing to their high content of minerals like potassium,
besides sodium, which can be utilised as a healthy sodium replacer in food. In addition …

Chronic low-grade inflammation is a feature of the pathophysiology of obesity and diabetes
in the CNS as well as peripheral tissues. Glial cells are critical mediators of the response to …

Metabolomics has emerged as a powerful new tool in precision medicine. No studies have
yet been published on the metabolomic changes in cerebrospinal fluid (CSF) produced by …

Memory CD8+ T cells participate in the fight against infection and tumorigenesis as well as
in autoimmune disease progression because of their efficient and rapid immune response …

Aim Extracellular ATP signalling is involved in many physiological and pathophysiological
processes in several tissues, including adipose tissue. Adipocytes have crucial functions in …

The innate immune system, as the host's first line of defense against intruders, plays a
critical role in recognizing, identifying, and reacting to a wide range of microbial intruders …

Extracellular ATP and adenosine are neuromodulators that regulate numerous neuronal
functions in the brain. Neuronal activity and brain insults such as ischemic and traumatic …

Purinergic signaling by extracellular ATP regulates a variety of cellular events and is
implicated in both normal physiology and pathophysiology. Several molecules have been …